The aim of the present study is to evaluate the quantitative contribution of passive permeability to P-glycoprotein-mediated (P-gp-mediated) efflux and the functional activity of P-gp in determining intestinal absorption of drugs, and demonstrate the relationship between efflux parameters and intestinal permeability. The associated datasets are available on QSAR world at: http://www.qsarworld.com/qsar-datasets-varma.php
Tom Gravestock, Karl Box, John Comer, Elizabeth Frake, Sam Judge and Rebeca Ruiz.
The “GI dissolution” method: a low volume, in vitro apparatus for assessing the dissolution/precipitation behaviour of an active pharmaceutical ingredient under biorelevant conditions, Anal. Methods, 2011, 3, 560.
Dipyridamole stress echocardiography: to be included in the Guidelines or to be abandoned from the clinical arena?, The International Journal of Cardiovascular Imaging