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14The novel isoxazoline ectoparasiticide lotilaner (Credelio???): a non-competitive antagonist specific to invertebrates ??-aminobutyric acid-gated chloride channels (GABACls), Parasites & Vectors A randomized, controlled field study to assess the efficacy and safety of lotilaner flavored chewable tablets (Credelio???) in eliminating fleas in client-owned dogs in the USA, Parasites & Vectors Laboratory evaluation of the speed of kill of lotilaner (Credelio???) against Ixodes ricinus ticks on dogs, Parasites & Vectors The intravenous and oral pharmacokinetics of lotilaner in dogs, Parasites & Vectors Laboratory evaluations of the immediate and sustained efficacy of lotilaner (Credelio???) against four common species of ticks affecting dogs in North America, Parasites & Vectors Laboratory evaluations of the immediate and sustained effectiveness of lotilaner (Credelio???) against three common species of ticks affecting dogs in Europe, Parasites & Vectors Safety evaluation of lotilaner in dogs after oral administration as flavoured chewable tablets (Credelio???), Parasites & Vectors A randomised, blinded, controlled field study to assess the efficacy and safety of lotilaner tablets (Credelio???) in controlling fleas in client-owned dogs in European countries, Parasites & Vectors Assessment of the onset of lotilaner (Credelio???) speed of kill of fleas on dogs, Parasites & Vectors Assessment of the speed of flea kill of lotilaner (Credelio???) throughout the month following oral administration to dogs, Parasites & Vectors