The aim of the present study is to evaluate the quantitative contribution of passive permeability to P-glycoprotein-mediated (P-gp-mediated) efflux and the functional activity of P-gp in determining intestinal absorption of drugs, and demonstrate the relationship between efflux parameters and intestinal permeability. The associated datasets are available on QSAR world at: http://www.qsarworld.com/qsar-datasets-varma.php
Eduardo Costa Figueiredo, Regina Sparrapan, Gustavo Braga Sanvido, Mariane Gonçalves Santos, Marco Aurélio Zezzi Arruda and Marcos Nogueira Eberlin.
Quantitation of drugs via molecularly imprinted polymer solid phase extraction and electrospray ionization mass spectrometry: benzodiazepines in human plasma, Analyst, 2011, 136, 3753.
So Sung-Sau, Karplus Martin.
Genetic Neural Networks for Quantitative Structure−Activity Relationships: Improvements and Application of Benzodiazepine Affinity for Benzodiazepine/GABAAReceptors, Journal of Medicinal Chemistry, 1996
Preparation of a Broadly Specific Monoclonal Antibody-Based Indirect Competitive ELISA for the Detection of Benzodiazepines in Edible Animal Tissues and Feed, Food Analytical Methods
Determination of flunitrazepam and nitrazepam in beverage samples by liquid chromatography with dual electrode detection using a carbon fibre veil electrode, Journal of Solid State Electrochemistry
Objective and subjective assessment of hangover during subacute administration of temazepam and nitrazepam to healthy subjects, European Journal of Clinical Pharmacology
Influence of Cyclodextrins on the in Vitro Drug Liberation of Rectal Suppositories Containing Benzodiazepine Derivates, Proceedings of the Eighth International Symposium on Cyclodextrins