ChemSpider 2D Image | (-)-Scopolamine methyl bromide | C18H24BrNO4

(-)-Scopolamine methyl bromide

  • Molecular FormulaC18H24BrNO4
  • Average mass398.292 Da
  • Monoisotopic mass397.088867 Da
  • ChemSpider ID10481908

  • Charge - Charge

    defined stereocentres - 6 of 6 defined stereocentres

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

(-)-Scopolamine methyl bromide
(-)-Scopolamine Methobromide
(-)-Tropic acid Ester with 6b,7b-Epoxy-3a-hydroxy-8-methyl-1aH,5aH-tropanium Bromide
(1a,2b,4b,5a,7b)-7-[(2S)-3-Hydroxy-1-oxo-2-phenylpropoxy]-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.02,4]nonane Bromide
(1R,2R,4S,5S,7s)-7-{[(2S)-3-Hydroxy-2-phenylpropanoyl]oxy}-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.02,4]nonanbromid [German] [ACD/IUPAC Name]
(1R,2R,4S,5S,7s)-7-{[(2S)-3-Hydroxy-2-phenylpropanoyl]oxy}-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.02,4]nonane bromide [ACD/IUPAC Name]
[7(S)-(1a,2b,4b,5a,7b)]-7-(3-Hydroxy-1-oxo-2-phenylpropoxy)-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.02,4]nonane Bromide
155-41-9 [RN]
205-844-5 [EINECS]
3-Oxa-9-azoniatricyclo[3.3.1.02,4]nonane, 7-[(2S)-3-hydroxy-1-oxo-2-phenylpropoxy]-9,9-dimethyl-, bromide, (1R,2R,4S,5S)- (1:1) [ACD/Index Name]
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Validated by Experts, Validated by Users, Non-Validated, Removed by Users

HSDB 5420 [DBID]
U 5036 [DBID]
MLS000069754 [DBID]
NSC 120606 [DBID]
NSC61809 [DBID]
SMR000058794 [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Chemical Class:

      A quaternary ammonium salt resulting from the reaction of the amino group of scopolamine with methyl bromide. ChEBI https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:61276, CHEBI:61276

    • Bio Activity:

      GPCR/G protein MedChem Express HY-B0344
      GPCR/G protein; Neuronal Signaling; MedChem Express HY-B0344
      mAChR MedChem Express HY-B0344
      Methscopolamine (Pamine) is a muscarinic acetylcholine receptor blocker. MedChem Express http://www.medchemexpress.com/Propylthiouracil.html, HY-B0344
      Methscopolamine (Pamine) is a muscarinic acetylcholine receptor blocker. ;Target: mAChRMethylscopolamine is an oral medication used along with other medications to treat peptic ulcers by reducing stomach acid secretion. With the advent of proton pump inhibitors and antihistamine medications it is rarely used for this. It can also be used for stomach or intestinal spasms, to reduce salivation, and to treat motion sickness. From Wikipedia.Methscopolamine (Pamine), an anti-acetylcholine drug, prevented ulcer formation, reduced further volume and acid output but produced a 3-4 fold increase in hexosamine concentration. Tissue (corpus and antrum) hexosamine was moderately reduced by restraint. In the corpus, this was counteracted by methscopolamine but antrum hexosamine was not influenced by this drug. The anti-ulcer property of methscopolamine may be due not only to its effect on acid secretion but also to the rise in gastric mucus concentration that it produced [1]. MedChem Express HY-B0344

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

No predicted properties have been calculated for this compound.

Click to predict properties on the Chemicalize site


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