ChemSpider 2D Image | glycopyrronium bromide | C19H28BrNO3

glycopyrronium bromide

  • Molecular FormulaC19H28BrNO3
  • Average mass398.335 Da
  • Monoisotopic mass397.125244 Da
  • ChemSpider ID11201
  • Charge - Charge


More details:



Featured data source



Validated by Experts, Validated by Users, Non-Validated, Removed by Users

3-[2-Cyclopentyl(hydroxy)phenylacetoxy]-1,1-dimethylpyrrolidinium bromide [ACD/IUPAC Name]
3-[2-Cyclopentyl(hydroxy)phenylacetoxy]-1,1-dimethylpyrrolidiniumbromid [German] [ACD/IUPAC Name]
3-{[cyclopentyl(hydroxy)phenylacetyl]oxy}-1,1-dimethylpyrrolidinium bromide
3-{[Cyclopentyl(hydroxy)phenylacetyl]oxy}-1,1-dimethylpyrrolidiniumbromid [German]
3-Hydroxy-1,1-dimethylpyrrolidinium bromide α-cyclopentylmandelate
596-51-0 [RN]
Bromure de 3-(2-cyclopentyl-2-hydroxy-2-phénylacétoxy)-1,1-diméthylpyrrolidinium [French] [ACD/IUPAC Name]
bromure de 3-{[cyclopentyl(hydroxy)phénylacétyl]oxy}-1,1-diméthylpyrrolidinium [French]
bromure de glycopyrronium [French] [INN]
bromuro de glicopirronio [Spanish] [INN]
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Validated by Experts, Validated by Users, Non-Validated, Removed by Users

AHR 504 [DBID]
AHR-504 [DBID]
D00540 [DBID]
NSC 250836 [DBID]
NSC 251251 [DBID]
NSC 251252 [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous
    • Appearance:

      WHITE CRYSTALLINE POWDER NIH Clinical Collection [SMR000469282]
    • Safety:

      TBC SynQuest 4H29-9-19
    • Target Organs:

      AChR antagonist TargetMol T2387
    • Chemical Class:

      A quaternary ammonium salt composed of 3-{[cyclopentyl(hydroxy)phenylacetyl]oxy}-1,1-dimethylpyrrolidin-1-ium and bromide ions in a 1:1 ratio. ChEBI CHEBI:90972
    • Bio Activity:

      Glycopyrrolate(Glycopyrronium Br) is a muscarinic competitive antagonist used as an antispasmodic.; IC50 Value:; Target: mAChR (Muscarinic acetylcholine receptor M1); in vitro: Glycopyrrolate showed no selectivity in its binding to the M1-M3 receptors. MedChem Express HY-17465
      Glycopyrrolate(Glycopyrronium Br) is a muscarinic competitive antagonist used as an antispasmodic.;IC50 Value:;Target: mAChR (Muscarinic acetylcholine receptor M1);In vitro: Glycopyrrolate showed no selectivity in its binding to the M1-M3 receptors. Kinetics studies, however, showed that glycopyrrolate dissociates slowly from HASM muscarinic receptors (60% protection against [3H]-NMS binding at 30 nM) compared to ipratropium bromide [1].;In vivo: Glycopyrrolate (1 mg) tablets were then administered, starting with one tablet daily the third week and increasing the daily dose by one tablet per week until a maximum of four tablets during week six and 4 days of week seven when the daily dose was reduced to two tablets for 3 days. glycopyrrolate can be given in controlled doses provided that an adequate medical assessment has been undertaken [2]. Glycopyrrolate has a slow and erratic absorption from the gastrointestinal system, but even low plasma levels are associated with a distinct MedChem Express HY-17465
      GPCR/G protein MedChem Express HY-17465
      GPCR/G protein; Neuronal Signaling; MedChem Express HY-17465
      mAChR MedChem Express HY-17465
      mAChR M1 TargetMol T2387
      Neuroscience TargetMol T2387

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module

No predicted properties have been calculated for this compound.

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