ChemSpider 2D Image | Anamorelin hydrochloride | C31H43ClN6O3

Anamorelin hydrochloride

  • Molecular FormulaC31H43ClN6O3
  • Average mass583.164 Da
  • Monoisotopic mass582.308533 Da
  • ChemSpider ID17231641

  • defined stereocentres - 2 of 2 defined stereocentres

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

3-{(2R)-3-{(3R)-3-Benzyl-3-[(trimethylhydrazino)carbonyl]-1-piperidinyl}-2-[(2-methylalanyl)amino]-3-oxopropyl}-1H-indole hydrochloride (1:1) [ACD/IUPAC Name]
3-{(2R)-3-{(3R)-3-Benzyl-3-[(triméthylhydrazino)carbonyl]-1-pipéridinyl}-2-[(2-méthylalanyl)amino]-3-oxopropyl}-1H-indole, chlorhydrate (1:1) [French] [ACD/IUPAC Name]
3-{(2R)-3-{(3R)-3-Benzyl-3-[(trimethylhydrazino)carbonyl]-1-piperidinyl}-2-[(2-methylalanyl)amino]-3-oxopropyl}-1H-indolhydrochlorid (1:1) [German] [ACD/IUPAC Name]
3-Piperidinecarboxylic acid, 1-[(2R)-2-[(2-amino-2-methyl-1-oxopropyl)amino]-3-(1H-indol-3-yl)-1-oxopropyl]-3-(phenylmethyl)-, 1,2,2-trimethylhydrazide, (3R)-, hydrochloride (1:1) [ACD/Index Name]
55F75LJQ0V
861998-00-7 [RN]
Anamorelin HCl
Anamorelin hydrochloride [USAN]
[861998-00-7] [RN]
2-amino-N-[(2R)-1-[(3R)-3-benzyl-3-[dimethylamino(methyl)carbamoyl]piperidin-1-yl]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-2-methylpropanamide
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Validated by Experts, Validated by Users, Non-Validated, Removed by Users

RC-1291 HCl [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Bio Activity:

      Anamorelin Hcl(RC1291; ONO-7643) is a synthetic orally active ghrelin receptor agonist which is under development for the management of non-small lung cancer associated cachexia/anorexia. MedChem Express http://www.medchemexpress.com/Anamorelin.html, HY-14734A
      Anamorelin Hcl(RC1291; ONO-7643) is a synthetic orally active ghrelin receptor agonist which is under development for the management of non-small lung cancer associated cachexia/anorexia. ;IC50 Value:;Target: ghrelin receptorAnamorelin hydrochloride is the orally bioavailable hydrochloride salt of a synthetic, small-molecule ghrelin mimetic with appetite-stimulating and anabolic activities. Anamorelin binds to and stimulates the growth hormone secretagogue receptor (GHSR) centrally, thereby mimicking the appetite-stimulating and growth hormone-releasing effects of grhelin. Stimulation of GHSR may also reduce the production of the pro-inflammatory cytokines TNF-alpha and interleukin-6, which may play a direct role in cancer-related loss of appetite. MedChem Express HY-14734A
      GHSR MedChem Express HY-14734A
      GPCR/G protein MedChem Express HY-14734A
      GPCR/G protein; MedChem Express HY-14734A

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

No predicted properties have been calculated for this compound.

Click to predict properties on the Chemicalize site


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