ChemSpider 2D Image | SRT1720 | C25H23N7OS

SRT1720

  • Molecular FormulaC25H23N7OS
  • Average mass469.561 Da
  • Monoisotopic mass469.168488 Da
  • ChemSpider ID20581461

More details:






Validated by Experts, Validated by Users, Non-Validated, Removed by Users

2-Quinoxalinecarboxamide, N-[2-[3-(1-piperazinylmethyl)imidazo[2,1-b]thiazol-6-yl]phenyl]- [ACD/Index Name]
N-{2-[3-(1-Piperazinylmethyl)imidazo[2,1-b][1,3]thiazol-6-yl]phenyl}-2-chinoxalincarboxamid [German] [ACD/IUPAC Name]
N-{2-[3-(1-Piperazinylmethyl)imidazo[2,1-b][1,3]thiazol-6-yl]phenyl}-2-quinoxalinecarboxamide [ACD/IUPAC Name]
N-{2-[3-(1-Pipérazinylméthyl)imidazo[2,1-b][1,3]thiazol-6-yl]phényl}-2-quinoxalinecarboxamide [French] [ACD/IUPAC Name]
N-{2-[3-(piperazin-1-ylmethyl)imidazo[2,1-b][1,3]thiazol-6-yl]phenyl}quinoxaline-2-carboxamide
SRT1720 [Wiki]
[1001645-58-4]
[925434-55-5]
1001645-58-4 [RN]
925434-55-5 [RN]
More...

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

CCRIS 4693 [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous
    • Appearance:

      Not Available Novochemy [NC-16823]
    • Safety:

      20/21/22 Novochemy [NC-16823]
      20/21/36/37/39 Novochemy [NC-16823]
      GHS07; GHS09 Novochemy [NC-16823]
      H332; H403 Novochemy [NC-16823]
      IRRITANT Matrix Scientific 093125
      P332+P313; P305+P351+P338 Novochemy [NC-16823]
      Warning Novochemy [NC-16823]
      Xn Novochemy [NC-16823]
    • Bio Activity:

      ; SRT1720 is a selective activator of human SIRT1 (EC1.5 = 0.16 ?M) versus the closest sirtuin homologues, SIRT2 and SIRT3(SIRT2: EC1.5 = 37 ?M; SIRT3: EC1.5 > 300 ?M). MedChem Express HY-10532
      Cell Cycle/DNA Damage MedChem Express HY-10532
      Cell Cycle/DNA Damage; MedChem Express HY-10532
      Sirtuin MedChem Express HY-10532

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module

Density: 1.5±0.1 g/cm3
Boiling Point:
Vapour Pressure:
Enthalpy of Vaporization:
Flash Point:
Index of Refraction: 1.779
Molar Refractivity: 134.3±0.5 cm3
#H bond acceptors: 8
#H bond donors: 2
#Freely Rotating Bonds: 5
#Rule of 5 Violations: 0
ACD/LogP: 3.78
ACD/LogD (pH 5.5): -0.28
ACD/BCF (pH 5.5): 1.00
ACD/KOC (pH 5.5): 1.00
ACD/LogD (pH 7.4): 1.43
ACD/BCF (pH 7.4): 2.86
ACD/KOC (pH 7.4): 24.73
Polar Surface Area: 116 Å2
Polarizability: 53.2±0.5 10-24cm3
Surface Tension: 65.9±7.0 dyne/cm
Molar Volume: 320.4±7.0 cm3

Click to predict properties on the Chemicalize site





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