ChemSpider 2D Image | Akt Inhibitor X | C20H26Cl2N2O

Akt Inhibitor X

  • Molecular FormulaC20H26Cl2N2O
  • Average mass381.339 Da
  • Monoisotopic mass380.142212 Da
  • ChemSpider ID21396100

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

10-DEBC hydrochloride
10H-Phenoxazine-10-butanamine, 2-chloro-N,N-diethyl-, hydrochloride (1:1) [ACD/Index Name]
201788-90-1 [RN]
4-(2-Chlor-10H-phenoxazin-10-yl)-N,N-diethyl-1-butanaminhydrochlorid (1:1) [German] [ACD/IUPAC Name]
4-(2-Chloro-10H-phenoxazin-10-yl)-N,N-diethyl-1-butanamine hydrochloride (1:1) [ACD/IUPAC Name]
4-(2-Chloro-10H-phénoxazin-10-yl)-N,N-diéthyl-1-butanamine, chlorhydrate (1:1) [French] [ACD/IUPAC Name]
4-(2-Chloro-10H-phenoxazin-10-yl)-N,N-diethylbutan-1-amine hydrochloride (1:1)
925681-41-0 [RN]
Akt Inhibitor X
[4-(2-CHLORO-10H-PHENOXAZIN-10-YL)BUTYL]DIETHYLAMINE HYDROCHLORIDE
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Validated by Experts, Validated by Users, Non-Validated, Removed by Users

925681-41-0201788-90-1 [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Bio Activity:

      Akt (Protein Kinase B) Tocris Bioscience 2558
      Enzymes Tocris Bioscience 2558
      Kinases Tocris Bioscience 2558
      Selective Akt/PKB inhibitor Tocris Bioscience 2558
      Selective inhibitor of Akt/PKB. Inhibits IGF-1-stimulated phosphorylation and activation of Akt (complete inhibition at 2.5 ?M), suppressing downstream activation of mTOR, p70 S6 kinase and S6 ribosom al protein. Shows no activity at PDK1, SGK1 or PI 3-kinase. Inhibits cell growth (IC50 ~ 2-6 ?M) and induces apoptosis in rhabdomyosarcoma cells. Tocris Bioscience 2558
      Selective inhibitor of Akt/PKB. Inhibits IGF-1-stimulated phosphorylation and activation of Akt (complete inhibition at 2.5 ?M), suppressing downstream activation of mTOR, p70 S6 kinase and S6 ribosomal protein. Shows no activity at PDK1, SGK1 or PI 3-kinase. Inhibits cell growth (IC50 ~ 2-6 ?M) and induces apoptosis in rhabdomyosarcoma cells. Tocris Bioscience 2558
      Selective inhibitor of Akt/PKB. Inhibits IGF-1-stimulated phosphorylation and activation of Akt (complete inhibition at 2.5 muM), suppressing downstream activation of mTOR, p70 S6 kinase and S6 ribosomal protein. Shows no activity at PDK1, SGK1 or PI 3-kinase. Inhibits cell growth (IC50 ~ 2-6 muM) and induces apoptosis in rhabdomyosarcoma cells. Tocris Bioscience 2558

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

No predicted properties have been calculated for this compound.

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