ChemSpider 2D Image | Alvespimycin hydrochloride | C32H49ClN4O8

Alvespimycin hydrochloride

  • Molecular FormulaC32H49ClN4O8
  • Average mass653.206 Da
  • Monoisotopic mass652.323914 Da
  • ChemSpider ID21396132

  • Double-bond stereo - Double-bond stereo

    defined stereocentres - 6 of 6 defined stereocentres

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

(4E,6Z,8S,9S,10E,12S,13R,14S,16R)-19-{[2-(Dimethylamino)ethyl]amino}-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl carbamate h ydrochloride (1:1) [ACD/IUPAC Name]
(4E,6Z,8S,9S,10E,12S,13R,14S,16R)-19-{[2-(Dimethylamino)ethyl]amino}-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-ylcarbamathydr ochlorid (1:1) [German] [ACD/IUPAC Name]
2-Azabicyclo[16.3.1]docosa-4,6,10,18,21-pentaene-3,20,22-trione, 9-[(aminocarbonyl)oxy]-19-[[2-(dimethylamino)ethyl]amino]-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-, (4E,6Z,8S,9S,10E,12S,13R,1 4S,16R)-, hydrochloride (1:1) [ACD/Index Name]
467214-21-7 [RN]
Alvespimycin hydrochloride [USAN]
Carbamate de (4E,6Z,8S,9S,10E,12S,13R,14S,16R)-19-{[2-(diméthylamino)éthyl]amino}-13-hydroxy-8,14-diméthoxy-4,10,12,16-tétraméthyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaén-9-y le, chlorhydrate (1:1) [French] [ACD/IUPAC Name]
[467214-21-7] [RN]
115-26-4 [RN]
17-Demethoxy-17-[[2-(dimethylamino)ethyl]amino]geldanamycin hydrochloride
17-Dimethylaminoethylamino-17-demethoxygeldanamycin hydrochloride
More...

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

17-DMAG · HCl [DBID]
17-DMAG hydrochloride [DBID]
612K359T69 [DBID]
BMS-826476 [DBID]
KOS-1022 [DBID]
NSC 707545 [DBID]
UNII:612K359T69 [DBID]
UNII-612K359T69 [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Safety:

      Sold with the permission of the NIH, US Patent 6,890,917 Tocris Bioscience 2610

    • Bio Activity:

      Water-soluble analog of 17-AAG (Cat. No. 1515) and geldanamycin (Cat. No. 1368). Binds the ATP binding site of Hsp90 and inhibits its chaperone activity. Displays more potent antitumor activity than 1 7-AAG (mean GI50 values are 53 and 123 nM for 17-DMAG and 17-AAG respectively). Tocris Bioscience 2610
      Water-soluble analog of 17-AAG (Cat. No. 1515) and geldanamycin (Cat. No. 1368). Binds the ATP binding site of Hsp90 and inhibits its chaperone activity. Displays more potent antitumor activity than 17-AAG (mean GI50 values are 53 and 123 nM for 17-DMAG and 17-AAG respectively). Tocris Bioscience 2610
      Water-soluble Hsp90 inhibitor Tocris Bioscience 2610

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

No predicted properties have been calculated for this compound.

Click to predict properties on the Chemicalize site


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