ChemSpider 2D Image | Harman | C32H30N2O4

Harman

  • Molecular FormulaC32H30N2O4
  • Average mass506.592 Da
  • Monoisotopic mass506.220551 Da
  • ChemSpider ID2281897

More details:

Featured data source
Natural Product Updates

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

2,5-Cyclohexadiene-1,4-dione, 2-[2-(1,1-dimethyl-2-propen-1-yl)-1H-indol-3-yl]-3,6-dihydroxy-5-[7-(3-methyl-2-buten-1-yl)-1H-indol-3-yl]- [ACD/Index Name]
2,5-Cyclohexadiene-1,4-dione, 2-[2-(1,1-dimethyl-2-propenyl)-1H-indol-3-yl]-3,6-dihydroxy-5-[7-(3-methyl-2-butenyl)-1H-indol-3-yl]-
2,5-Dihydroxy-3-[2-(2-methyl-3-buten-2-yl)-1H-indol-3-yl]-6-[7-(3-methyl-2-buten-1-yl)-1H-indol-3-yl]-1,4-benzochinon [German] [ACD/IUPAC Name]
2,5-Dihydroxy-3-[2-(2-methyl-3-buten-2-yl)-1H-indol-3-yl]-6-[7-(3-methyl-2-buten-1-yl)-1H-indol-3-yl]-1,4-benzoquinone [ACD/IUPAC Name]
2,5-Dihydroxy-3-[2-(2-méthyl-3-butén-2-yl)-1H-indol-3-yl]-6-[7-(3-méthyl-2-butén-1-yl)-1H-indol-3-yl]-1,4-benzoquinone [French] [ACD/IUPAC Name]
2,5-Dihydroxy-3-[2-(2-methylbut-3-en-2-yl)-1H-indol-3-yl]-6-[7-(3-methylbut-2-en-1-yl)-1H-indol-3-yl]-1,4-benzoquinone
2,5-dihydroxy-3-[2-(2-methylbut-3-en-2-yl)-1H-indol-3-yl]-6-[7-(3-methylbut-2-en-1-yl)-1H-indol-3-yl]cyclohexa-2,5-diene-1,4-dione
2-[2-(1,1-dimethyl-2-propen-1-yl)-1H-indol-3-yl]-3,6-dihydroxy-5-[7-(3-methyl-2-buten-1-yl)-1H-indol-3-yl]-2,5-cyclohexadiene-1,4-dione
78860-34-1 [RN]
Demethylasterriquinone B1
More...

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

AIDS222536 [DBID]
AIDS-222536 [DBID]
NCGC00025307-01 [DBID]
Tocris-1819 [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Bio Activity:

      Enzyme-Linked Receptors Tocris Bioscience 1819
      Insulin and insulin-like Receptors Tocris Bioscience 1819
      Receptor Tyrosine Kinases (RTKs) Tocris Bioscience 1819
      Selective insulin receptor (IR) activator (EC50 values are 3 - 6 ?M for IRTK and 100 ?M for IGF1R and EGFR). Increases IR ? subunit tyrosine phosphorylation and activation of PI 3-kinase and Akt, but not ERK. Induces glucose uptake in adipocytes and skeletal muscle in vitro, without enhancing vascular proliferation. Binds GAPDH. Also activates Trk by interacting at a site distinct from the neurotrophin-binding site. Tocris Bioscience 1819
      Selective insulin receptor (IR) activator (EC50 values are 3 - 6 muM for IRTK and 100 muM for IGF1R and EGFR). Increases IR beta subunit tyrosine phosphorylation and activation of PI 3-kinase and Akt, but not ERK. Induces glucose uptake in adipocytes and skeletal muscle in vitro, without enhancing vascular proliferation. Binds GAPDH. Also activates Trk by interacting at a site distinct from the neurotrophin-binding site. Tocris Bioscience 1819
      Selective insulin receptor (IR) activator/mimetic (EC50 values are 3 - 6 ?M for IRTK and 100 ?M for IGF1R and EGFR). Increases IR ? subunit tyrosine phosphorylation and downstream activation of PI 3-k inase and Akt, but not ERK. Induces glucose uptake in adipocytes and skeletal muscle in vitro, without enhancing vascular proliferation. Binds GAPDH. Tocris Bioscience 1819
      Selective insulin RTK activator Tocris Bioscience 1819

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

Density: 1.3±0.1 g/cm3
Boiling Point: 780.2±60.0 °C at 760 mmHg
Vapour Pressure: 0.0±2.8 mmHg at 25°C
Enthalpy of Vaporization: 119.1±3.0 kJ/mol
Flash Point: 425.6±32.9 °C
Index of Refraction: 1.720
Molar Refractivity: 149.8±0.3 cm3
#H bond acceptors: 6
#H bond donors: 4
#Freely Rotating Bonds: 6
#Rule of 5 Violations: 2
ACD/LogP: 6.39
ACD/LogD (pH 5.5): 2.09
ACD/BCF (pH 5.5): 3.07
ACD/KOC (pH 5.5): 7.26
ACD/LogD (pH 7.4): 1.21
ACD/BCF (pH 7.4): 1.00
ACD/KOC (pH 7.4): 1.00
Polar Surface Area: 106 Å2
Polarizability: 59.4±0.5 10-24cm3
Surface Tension: 68.7±3.0 dyne/cm
Molar Volume: 379.3±3.0 cm3

Click to predict properties on the Chemicalize site


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