ChemSpider 2D Image | Corylifol A | C25H26O4

Corylifol A

  • Molecular FormulaC25H26O4
  • Average mass390.471 Da
  • Monoisotopic mass390.183105 Da
  • ChemSpider ID22913562

  • Double-bond stereo - Double-bond stereo

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

3-{3-[(2E)-3,7-Dimethyl-2,6-octadien-1-yl]-4-hydroxyphenyl}-7-hydroxy-4H-chromen-4-on [German] [ACD/IUPAC Name]
3-{3-[(2E)-3,7-Dimethyl-2,6-octadien-1-yl]-4-hydroxyphenyl}-7-hydroxy-4H-chromen-4-one [ACD/IUPAC Name]
3-{3-[(2E)-3,7-Diméthyl-2,6-octadién-1-yl]-4-hydroxyphényl}-7-hydroxy-4H-chromén-4-one [French] [ACD/IUPAC Name]
4H-1-Benzopyran-4-one, 3-[3-[(2E)-3,7-dimethyl-2,6-octadien-1-yl]-4-hydroxyphenyl]-7-hydroxy- [ACD/Index Name]
775351-88-7 [RN]
Corylifol A
[775351-88-7] [RN]
3-[3-[(2E)-3,7-DIMETHYL-2,6-OCTADIEN-1-YL]-4-HYDROXYPHENYL]-7-HYDROXY-4H-1-BENZOPYRAN-4-ONE
3-[3-[(2E)-3,7-dimethylocta-2,6-dienyl]-4-hydroxyphenyl]-7-hydroxychromen-4-one
877402-44-3 [RN]
More...
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Bio Activity:

      Corylifol A is a phenolic compounds isolated from Psoralea corylifolia; inhibits IL-6-induced STAT3 activation and phosphorylation(IC50=0.8 uM). MedChem Express
      Corylifol A is a phenolic compounds isolated from Psoralea corylifolia; inhibits IL-6-induced STAT3 activation and phosphorylation(IC50=0.8 uM).; IC50 value: 0.8 uM [1]; Target: STAT3 inhibitor; Corylifol A showed an inhibitory effect on IL-6-induced STAT3 promoter activity in Hep3B cells with IC50 value of 0.81 ? 0.15 uM, also inhibited STAT3 phosphorylation induced by IL-6 in Hep3B cells [1]. MedChem Express HY-N0897
      JAK/STAT Signaling MedChem Express HY-N0897
      JAK/STAT Signaling; MedChem Express HY-N0897
      STAT MedChem Express HY-N0897

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

Density: 1.2±0.1 g/cm3
Boiling Point: 609.3±55.0 °C at 760 mmHg
Vapour Pressure: 0.0±1.8 mmHg at 25°C
Enthalpy of Vaporization: 93.8±3.0 kJ/mol
Flash Point: 208.8±25.0 °C
Index of Refraction: 1.615
Molar Refractivity: 114.4±0.3 cm3
#H bond acceptors: 4
#H bond donors: 2
#Freely Rotating Bonds: 6
#Rule of 5 Violations: 1
ACD/LogP: 6.91
ACD/LogD (pH 5.5): 5.98
ACD/BCF (pH 5.5): 20366.91
ACD/KOC (pH 5.5): 41823.64
ACD/LogD (pH 7.4): 5.40
ACD/BCF (pH 7.4): 5350.86
ACD/KOC (pH 7.4): 10988.05
Polar Surface Area: 67 Å2
Polarizability: 45.3±0.5 10-24cm3
Surface Tension: 50.3±3.0 dyne/cm
Molar Volume: 327.8±3.0 cm3

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