ChemSpider 2D Image | (E)-Tamoxifen citrate | C32H37NO8

(E)-Tamoxifen citrate

  • Molecular FormulaC32H37NO8
  • Average mass563.638 Da
  • Monoisotopic mass563.251892 Da
  • ChemSpider ID2298260

  • Double-bond stereo - Double-bond stereo

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

(E)-Tamoxifen citrate
13002-65-8 [RN]
2-{4-[(1E)-1,2-Diphenyl-1-buten-1-yl]phenoxy}-N,N-dimethylethanamine 2-hydroxy-1,2,3-propanetricarboxylate (1:1) [ACD/IUPAC Name]
2-{4-[(1E)-1,2-Diphenylbut-1-en-1-yl]phenoxy}-N,N-dimethylethanamine 2-hydroxypropane-1,2,3-tricarboxylate (1:1)
2-Hydroxy-1,2,3-propantricarbonsäure --2-{4-[(1E)-1,2-diphenyl-1-buten-1-yl]phenoxy}-N,N-dimethylethanamin (1:1) [German] [ACD/IUPAC Name]
76487-65-5 [RN]
Acide 2-hydroxy-1,2,3-propanetricarboxylique - 2-{4-[(1E)-1,2-diphényl-1-butén-1-yl]phénoxy}-N,N-diméthyléthanamine (1:1) [French] [ACD/IUPAC Name]
Ethanamine, 2-[4-[(1E)-1,2-diphenyl-1-buten-1-yl]phenoxy]-N,N-dimethyl-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1) (salt) [ACD/Index Name]
Tamoxifen [Wiki]
Tamoxifen citrate [JAN] [USAN]
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  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Bio Activity:

      <p>Citrate salt of Tamoxifen, which is an estrogen receptor antagonist and partial agonist. It is also a potent chloride channel HSV-1 inhibitor and is blood brain barrier permeable.</p> <p>Tamoxifen inhibits tumor growth and induces apoptosis in breast cancer cells. It also selectively inhibits sterol biosynthesis (IC<sub>50</sub> = 1000 nM) and shows neuroprotective potential.</p> <p>It is used in gene editing in which tamoxifen (Tm)-inducible Cre recombinases are widely used to perform gene inactivation and lineage tracing studies in mice.</p> <p>It can also switch on the inducible CRISPR-Cas9 system (iCas).</p> Hello Bio HB0602
      Biochemicals & small molecules/Antagonists & inhibitors Hello Bio HB0602
      Estrogen receptor antagonist and also partial agonist. Also potent chloride channel HSV-1 inhibitor. Blood brain barrier permeable. Inhibits tumor growth and induces apoptosis in breast cancer cells. Selectively inhibits sterol biosynthesis (IC<sub>50</sub> = 1000 nM). Shows neuroprotective potential. Hello Bio HB0602
      Estrogen receptor antagonist/ partial agonist Hello Bio HB0602
      Receptors & Transporters/Nuclear hormone/Estrogen and related/Non-selective Hello Bio HB0602

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

No predicted properties have been calculated for this compound.

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