ChemSpider 2D Image | 6,7-Dimethoxy-4-[N-(3-chlorophenyl)amino]quinazoline hydrochloride | C16H15Cl2N3O2

6,7-Dimethoxy-4-[N-(3-chlorophenyl)amino]quinazoline hydrochloride

  • Molecular FormulaC16H15Cl2N3O2
  • Average mass352.215 Da
  • Monoisotopic mass351.054138 Da
  • ChemSpider ID2299488

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

170449-18-0 [RN]
4-Quinazolinamine, N-(3-chlorophenyl)-6,7-dimethoxy-, hydrochloride (1:1) [ACD/Index Name]
6,7-Dimethoxy-4-[N-(3-chlorophenyl)amino]quinazoline hydrochloride
N-(3-Chlorophenyl)-6,7-dimethoxy-4-quinazolinamine hydrochloride (1:1) [ACD/IUPAC Name]
N-(3-Chlorophényl)-6,7-diméthoxy-4-quinazolinamine, chlorhydrate (1:1) [French] [ACD/IUPAC Name]
N-(3-Chlorophenyl)-6,7-dimethoxyquinazolin-4-amine hydrochloride (1:1)
N-(3-Chlorphenyl)-6,7-dimethoxy-4-chinazolinaminhydrochlorid (1:1) [German] [ACD/IUPAC Name]
[170449-18-0] [RN]
153436-53-4 [RN]
4-(3-Chloroanilino)-6,7-dimethoxyquinazoline HCl
More...

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

AG 1478 hydrochloride [DBID]
AG 1478 [DBID]
AG-1478 [DBID]
AG-1478 hydrochloride [DBID]
CCRIS 4693 [DBID]
Tyrphostin AG 1478 [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Safety:

      Sold with the permission of AstraZeneca UK Ltd. Tocris Bioscience 1276

    • Bio Activity:

      EGFR Tocris Bioscience 1276
      Enzyme-Linked Receptors Tocris Bioscience 1276
      Highly potent EGFR-kinase inhibitor Tocris Bioscience 1276
      Potent and selective inhibitor of epidermal growth factor receptor kinase (IC50 values 3 nM for EGFR and > 100 ?M for ErbB2 and PDGFR). Inhibits proliferation of NCI-H2170 NSCLC cells in vitro (IC50 = 1 ?M). Tocris Bioscience 1276
      Potent and selective inhibitor of epidermal growth factor receptor kinase (IC50 values 3 nM for EGFR and > 100 ?M for ErbB2 and PDGFR). Inhibits proliferation of NCI-H2170 NSCLC cells in vitro (IC50 = 1 ?M). Tocris Bioscience 1276
      Potent and selective inhibitor of epidermal growth factor receptor kinase (IC50 values 3 nM for EGFR and > 100 muM for ErbB2 and PDGFR). Inhibits proliferation of NCI-H2170 NSCLC cells in vitro (IC50 = 1 muM). Tocris Bioscience 1276
      Receptor Tyrosine Kinases (RTKs) Tocris Bioscience 1276

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

No predicted properties have been calculated for this compound.

Click to predict properties on the Chemicalize site


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