ChemSpider 2D Image | Salermide | C26H22N2O2

Salermide

  • Molecular FormulaC26H22N2O2
  • Average mass394.465 Da
  • Monoisotopic mass394.168121 Da
  • ChemSpider ID24608652

  • Double-bond stereo - Double-bond stereo

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

1105698-15-4 [RN]
Benzeneacetamide, N-[3-[[(1E)-(2-hydroxy-1-naphthalenyl)methylene]amino]phenyl]-α-methyl- [ACD/Index Name]
MFCD12912446
N-(3-{(E)-[(2-Hydroxy-1-naphthyl)methylen]amino}phenyl)-2-phenylpropanamid [German] [ACD/IUPAC Name]
N-(3-{(E)-[(2-Hydroxy-1-naphthyl)methylene]amino}phenyl)-2-phenylpropanamide [ACD/IUPAC Name]
N-(3-{(E)-[(2-Hydroxy-1-naphtyl)méthylène]amino}phényl)-2-phénylpropanamide [French] [ACD/IUPAC Name]
N-{3-[(2-Hydroxy-naphthalen-1-ylmethylene)-amino]-phenyl}-2-phenyl-propionamide
N-{3-[(E)-[(2-HYDROXYNAPHTHALEN-1-YL)METHYLIDENE]AMINO]PHENYL}-2-PHENYLPROPANAMIDE
Salermide
(E)-N-(3-(((2-hydroxynaphthalen-1-yl)methylene)amino)phenyl)-2-phenylpropanamide
More...
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Bio Activity:

      Deacetylases Tocris Bioscience 4127
      Enzymes Tocris Bioscience 4127
      Sir2-like Family Deacetylases Tocris Bioscience 4127
      SIRT1 and SIRT2 inhibitor Tocris Bioscience 4127
      SIRT1 and SIRT2 inhibitor. Exhibits a stronger inhibitory effect on SIRT2 than on SIRT1 in vitro. Induces the reactivation of proapoptotic genes repressed by SIRT1 and causes massive apoptosis in canc er cells within 24 hours. Tocris Bioscience 4127
      SIRT1 and SIRT2 inhibitor. Exhibits a stronger inhibitory effect on SIRT2 than on SIRT1 in vitro. Induces the reactivation of proapoptotic genes repressed by SIRT1 and causes massive apoptosis in cancer cells within 24 hours. Tocris Bioscience 4127

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

Density: 1.2±0.1 g/cm3
Boiling Point: 666.7±50.0 °C at 760 mmHg
Vapour Pressure: 0.0±2.1 mmHg at 25°C
Enthalpy of Vaporization: 101.6±3.0 kJ/mol
Flash Point: 357.0±30.1 °C
Index of Refraction: 1.623
Molar Refractivity: 119.8±0.5 cm3
#H bond acceptors: 4
#H bond donors: 2
#Freely Rotating Bonds: 5
#Rule of 5 Violations: 1
ACD/LogP: 5.40
ACD/LogD (pH 5.5): 5.24
ACD/BCF (pH 5.5): 5618.16
ACD/KOC (pH 5.5): 16773.52
ACD/LogD (pH 7.4): 5.19
ACD/BCF (pH 7.4): 5034.35
ACD/KOC (pH 7.4): 15030.53
Polar Surface Area: 62 Å2
Polarizability: 47.5±0.5 10-24cm3
Surface Tension: 45.4±7.0 dyne/cm
Molar Volume: 339.9±7.0 cm3

Click to predict properties on the Chemicalize site


Advertisement