ChemSpider 2D Image | Ampkinone | C31H23NO6

Ampkinone

  • Molecular FormulaC31H23NO6
  • Average mass505.517 Da
  • Monoisotopic mass505.152527 Da
  • ChemSpider ID26363426

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

[1]Benzopyrano[3,4-e]isoindole-1,3(2H,4H)-dione, 2-(4-benzoylphenyl)-6-hydroxy-7-methoxy-4,4-dimethyl- [ACD/Index Name]
1233082-79-5 [RN]
2-(4-benzoylphenyl)-6-hydroxy-7-methoxy-4,4-dimethyl-1H,2H,3H,4H-chromeno[3,4-e]isoindole-1,3-dione
2-(4-Benzoylphenyl)-6-hydroxy-7-methoxy-4,4-dimethylchromeno[3,4-e]isoindol-1,3(2H,4H)-dion [German] [ACD/IUPAC Name]
2-(4-Benzoylphenyl)-6-hydroxy-7-methoxy-4,4-dimethylchromeno[3,4-e]isoindole-1,3(2H,4H)-dione [ACD/IUPAC Name]
2-(4-Benzoylphényl)-6-hydroxy-7-méthoxy-4,4-diméthylchroméno[3,4-e]isoindole-1,3(2H,4H)-dione [French] [ACD/IUPAC Name]
2-(4-benzoylphenyl)-6-hydroxy-7-methoxy-4,4-dimethylchromeno[3,4-e]isoindole-1,3-dione
Ampkinone
2-(4-benzoylphenyl)-6-hydroxy-7-methoxy-4,4-dimethyl-[1]benzopyrano[3,4-e]isoindole-1,3(2H,4H)-dione
2-?(4-?benzoylphenyl)?-?6-?hydroxy-?7-?methoxy-?4,?4-?dimethyl-[1]?Benzopyrano[3,?4-?e]?isoindole-?1,?3(2H,?4H)?-?dione
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  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Bio Activity:

      AMPK MedChem Express HY-12831
      Ampkinone is a small molecule activator of AMPK; stimulate functional activation of AMPK via the phosphorylation at Thr172 in cultured L6 muscle cells with an EC50 value of 4.3 ?M, enhancing glucose uptake by 3.2-fold.; IC50 value: 4.3 uM(EC50) [1]; Target: AMPK acivator; Ampkinone stimulated the phosphorylation of AMPK via the indirect activation of AMPK in various cell lines. MedChem Express HY-12831
      PI3K/Akt/mTOR MedChem Express HY-12831
      PI3K/Akt/mTOR; MedChem Express HY-12831

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

Density: 1.4±0.1 g/cm3
Boiling Point: 732.7±70.0 °C at 760 mmHg
Vapour Pressure: 0.0±2.5 mmHg at 25°C
Enthalpy of Vaporization: 110.7±3.0 kJ/mol
Flash Point: 396.9±35.7 °C
Index of Refraction: 1.666
Molar Refractivity: 138.9±0.3 cm3
#H bond acceptors: 7
#H bond donors: 1
#Freely Rotating Bonds: 4
#Rule of 5 Violations: 1
ACD/LogP: 4.70
ACD/LogD (pH 5.5): 4.23
ACD/BCF (pH 5.5): 966.23
ACD/KOC (pH 5.5): 4767.43
ACD/LogD (pH 7.4): 4.22
ACD/BCF (pH 7.4): 943.53
ACD/KOC (pH 7.4): 4655.41
Polar Surface Area: 93 Å2
Polarizability: 55.1±0.5 10-24cm3
Surface Tension: 57.9±3.0 dyne/cm
Molar Volume: 373.4±3.0 cm3

Click to predict properties on the Chemicalize site


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