ChemSpider 2D Image | Flumatinib mesylate | C30H33F3N8O4S

Flumatinib mesylate

  • Molecular FormulaC30H33F3N8O4S
  • Average mass658.694 Da
  • Monoisotopic mass658.229736 Da
  • ChemSpider ID30922985

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

4-[(4-Methyl-1-piperazinyl)methyl]-N-(6-methyl-5-{[4-(3-pyridinyl)-2-pyrimidinyl]amino}-3-pyridinyl)-3-(trifluoromethyl)benzamide methanesulfonate (1:1) [ACD/IUPAC Name]
895519-91-2 [RN]
Acide méthanesulfonique - 4-[(4-méthyl-1-pipérazinyl)méthyl]-N-(6-méthyl-5-{[4-(3-pyridinyl)-2-pyrimidinyl]amino}-3-pyridinyl)-3-(trifluorométhyl)benzamide (1:1) [French] [ACD/IUPAC Name]
Benzamide, 4-[(4-methyl-1-piperazinyl)methyl]-N-[6-methyl-5-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-3-pyridinyl]-3-(trifluoromethyl)-, methanesulfonate (1:1) [ACD/Index Name]
Flumatinib mesylate
Methansulfonsäure --4-[(4-methyl-1-piperazinyl)methyl]-N-(6-methyl-5-{[4-(3-pyridinyl)-2-pyrimidinyl]amino}-3-pyridinyl)-3-(trifluormethyl)benzamid (1:1) [German] [ACD/IUPAC Name]
N-(6-METHYL-5-{[4-(PYRIDIN-3-YL)PYRIMIDIN-2-YL]AMINO}PYRIDIN-3-YL)-4-[(4-METHYLPIPERAZIN-1-YL)METHYL]-3-(TRIFLUOROMETHYL)BENZAMIDE; METHANESULFONIC ACID
(2R)-5-[[amino(nitramido)methylene]amino]-2-(tert-butoxycarbonylamino)pentanoic acid;Nα-Boc-Nω-nitro-D-arginine
895519-91-2 (mesylate)
BenzaMide, 4-[(4-Methyl-1-piperazinyl)Methyl]-N-[6-Methyl-5-[[4-(3-pyridinyl)-2-pyriMidinyl]aMino]-3-pyridinyl]-3-(trifluoroMethyl)-, MonoMethanesulfonate (9CI)
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Validated by Experts, Validated by Users, Non-Validated, Removed by Users

95Y8L63NBC [DBID]
UNII:95Y8L63NBC [DBID]
UNII-95Y8L63NBC [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Bio Activity:

      Bcr-Abl MedChem Express HY-13905
      Bcr-Abl c-Kit PDGFR MedChem Express HY-13905
      Flumatinib mesylate (HH-GV-678 mesylate), a derivative of imatinib, is a multi-kinase inhibitor with IC50 Values of 1.2 nM, 307.6 nM and 2662 nM for c-Abl, PDGFR? and c-Kit respectively.; IC50 Value: 1.2 nM (c-Abl); 307.6 nM(PDGFR?); 2662 nM (c-Kit) [1]; Target: c-Abl; c-Kit; PDGRF?; in vitro: HH-GV-678 can predominantly inhibit the autophosphorylation of Bcr-Abl in K562 cell. MedChem Express HY-13905
      Protein Tyrosine Kinase/RTK MedChem Express HY-13905
      Protein Tyrosine Kinase/RTK; MedChem Express HY-13905

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

No predicted properties have been calculated for this compound.

Click to predict properties on the Chemicalize site


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