ChemSpider 2D Image | cerdulatinib | C20H27N7O3S

cerdulatinib

  • Molecular FormulaC20H27N7O3S
  • Average mass445.539 Da
  • Monoisotopic mass445.189606 Da
  • ChemSpider ID32822046

More details:






Validated by Experts, Validated by Users, Non-Validated, Removed by Users

1198300-79-6 [RN]
4-(Cyclopropylamino)-2-({4-[4-(ethylsulfonyl)-1-piperazinyl]phenyl}amino)-5-pyrimidincarboxamid [German] [ACD/IUPAC Name]
4-(Cyclopropylamino)-2-({4-[4-(ethylsulfonyl)-1-piperazinyl]phenyl}amino)-5-pyrimidinecarboxamide [ACD/IUPAC Name]
4-(Cyclopropylamino)-2-({4-[4-(éthylsulfonyl)-1-pipérazinyl]phényl}amino)-5-pyrimidinecarboxamide [French] [ACD/IUPAC Name]
5-Pyrimidinecarboxamide, 4-(cyclopropylamino)-2-[[4-[4-(ethylsulfonyl)-1-piperazinyl]phenyl]amino]- [ACD/Index Name]
9987
cerdulatinib [INN]
cerdulatinib [French] [INN]
cerdulatinib [Spanish] [INN]
cerdulatinibum [Latin] [INN]
More...
  • Experimental Physico-chemical Properties
  • Miscellaneous
    • Target Organs:

      JAK inhibitor; Syk inhibitor TargetMol T2487
    • Bio Activity:

      Cerdulatinib(PRT-062070; PRT2070) is an novel oral dual Syk/JAK inhibitor. MedChem Express
      Cerdulatinib(PRT-062070; PRT2070) is an novel oral dual Syk/JAK inhibitor.; IC50 value:; Target: Syk/JAK inhibitor; Cerdulatinib is currently being studied in patients with genetically-defined hematologic cancers, as well as for patients who have failed therapy due to relapse or acquired mutations. MedChem Express HY-15999
      Cerdulatinib(PRT-062070; PRT2070) is an novel oral dual Syk/JAK inhibitor.;IC50 value:;Target: Syk/JAK inhibitorCerdulatinib is currently being studied in patients with genetically-defined hematologic cancers, as well as for patients who have failed therapy due to relapse or acquired mutations. MedChem Express HY-15999
      JAK MedChem Express HY-15999
      JAK Syk MedChem Express HY-15999
      JAK/STAT Signaling MedChem Express HY-15999
      JAK/STAT Signaling; Angiogenesis TargetMol T2487
      JAK/STAT Signaling; Protein Tyrosine Kinase/RTK; MedChem Express HY-15999
      Syk/JAK TargetMol T2487

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module

Density: 1.4±0.1 g/cm3
Boiling Point: 741.9±70.0 °C at 760 mmHg
Vapour Pressure: 0.0±2.5 mmHg at 25°C
Enthalpy of Vaporization: 108.2±3.0 kJ/mol
Flash Point: 402.5±35.7 °C
Index of Refraction: 1.683
Molar Refractivity: 116.9±0.4 cm3
#H bond acceptors: 10
#H bond donors: 4
#Freely Rotating Bonds: 8
#Rule of 5 Violations: 1
ACD/LogP: 0.37
ACD/LogD (pH 5.5): 0.81
ACD/BCF (pH 5.5): 1.83
ACD/KOC (pH 5.5): 38.08
ACD/LogD (pH 7.4): 1.33
ACD/BCF (pH 7.4): 5.97
ACD/KOC (pH 7.4): 123.97
Polar Surface Area: 142 Å2
Polarizability: 46.3±0.5 10-24cm3
Surface Tension: 81.6±5.0 dyne/cm
Molar Volume: 308.3±5.0 cm3

Click to predict properties on the Chemicalize site






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