ChemSpider 2D Image | ADX71743 | C17H19NO2

ADX71743

  • Molecular FormulaC17H19NO2
  • Average mass269.338 Da
  • Monoisotopic mass269.141571 Da
  • ChemSpider ID34980747

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

1431641-29-0 [RN]
4(5H)-Benzoxazolone, 6-(2,4-dimethylphenyl)-2-ethyl-6,7-dihydro- [ACD/Index Name]
6-(2,4-Dimethylphenyl)-2-ethyl-6,7-dihydro-1,3-benzoxazol-4(5H)-on [German] [ACD/IUPAC Name]
6-(2,4-Dimethylphenyl)-2-ethyl-6,7-dihydro-1,3-benzoxazol-4(5H)-one [ACD/IUPAC Name]
6-(2,4-Diméthylphényl)-2-éthyl-6,7-dihydro-1,3-benzoxazol-4(5H)-one [French] [ACD/IUPAC Name]
6-(2,4-Dimethylphenyl)-2-ethyl-6,7-dihydrobenzo[d]oxazol-4(5H)-one
ADX71743
MFCD30474715
(?)-ADX 71743
(±)-ADX 71743
More...
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Bio Activity:

      7-TM Receptors Tocris Bioscience 5715
      Glutamate (Metabotropic) Group III Receptors Tocris Bioscience 5715
      Glutamate (Metabotropic) Receptors Tocris Bioscience 5715
      Negative allosteric modulator at mGlu7 (IC50 = 300 nM). Blocks high frequency-induced LTP at SC-CA1 synapses in hippocampal slices in vitro. Increases evoked excitatory postsynaptic currents (eEPSCs) in mice. Brain penetrant. Tocris Bioscience 5715
      Negative allosteric modulator at mGlu7; brain penetrant Tocris Bioscience 5715

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

Density: 1.1±0.1 g/cm3
Boiling Point: 405.1±24.0 °C at 760 mmHg
Vapour Pressure: 0.0±0.9 mmHg at 25°C
Enthalpy of Vaporization: 65.7±3.0 kJ/mol
Flash Point: 198.8±22.9 °C
Index of Refraction: 1.561
Molar Refractivity: 77.2±0.3 cm3
#H bond acceptors: 3
#H bond donors: 0
#Freely Rotating Bonds: 2
#Rule of 5 Violations: 0
ACD/LogP: 3.69
ACD/LogD (pH 5.5): 4.15
ACD/BCF (pH 5.5): 835.65
ACD/KOC (pH 5.5): 4297.20
ACD/LogD (pH 7.4): 4.15
ACD/BCF (pH 7.4): 835.65
ACD/KOC (pH 7.4): 4297.21
Polar Surface Area: 43 Å2
Polarizability: 30.6±0.5 10-24cm3
Surface Tension: 44.4±3.0 dyne/cm
Molar Volume: 238.3±3.0 cm3

Click to predict properties on the Chemicalize site


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