ChemSpider 2D Image | Butenafine hydrochloride | C23H28ClN

Butenafine hydrochloride

  • Molecular FormulaC23H28ClN
  • Average mass353.928 Da
  • Monoisotopic mass353.191040 Da
  • ChemSpider ID391957

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

1-(4-tert-Butylphenyl)-N-methyl-N-(1-naphthylmethyl)methanamine hydrochloride (1:1)
1-(4-tert-butylphenyl)-N-methyl-N-(naphthalen-1-ylmethyl)methanamine hydrochloride
1-(4-tert-butylphenyl)-N-methyl-N-(naphthalen-1-ylmethyl)methanamine hydrochloride (1:1)
1-(4-tert-Butylphenyl)-N-methyl-N-(naphthalen-1-ylmethyl)methanaminhydrochlorid
1-[4-(1,1-diméthyléthyl)phényl]-N-méthyl-N-(naphtalén-1-ylméthyl)méthanamine chlorhydrate
101827-46-7 [RN]
1-Naphthalenemethanamine, N-((4-(1,1-dimethylethyl)phenyl)methyl)-N-methyl-, hydrochloride
1-naphthalenemethanamine, N-[[4-(1,1-dimethylethyl)phenyl]methyl]-N-methyl-, hydrochloride
1-Naphthalenemethanamine, N-[[4-(1,1-dimethylethyl)phenyl]methyl]-N-methyl-, hydrochloride (1:1) [ACD/Index Name]
Butenafine (Hydrochloride)
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Validated by Experts, Validated by Users, Non-Validated, Removed by Users

C12490 [DBID]
D01093 [DBID]
KP-363 [DBID]
KS-1035 [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Target Organs:

      Antibiotic TargetMol T1217

    • Chemical Class:

      The hydrochloride salt of butenafine. An inhibitor of squalene epoxidase, an enzyme responsible for the creation of sterols needed in fungal cell membranes, it is used for treatment of dermatological fungal infections. ChEBI https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:31325, CHEBI:31325

    • Bio Activity:

      Antifungal MedChem Express HY-17396
      Anti-infection MedChem Express HY-17396
      Anti-infection; MedChem Express HY-17396
      Butenafine hydrochloride is a synthetic benzylamine antifungal, works by inhibiting the synthesis of sterols by inhibiting squalene epoxidase. MedChem Express
      Butenafine hydrochloride is a synthetic benzylamine antifungal, works by inhibiting the synthesis of sterols by inhibiting squalene epoxidase.; IC50 Value: ; Target: Antifungal; squalene epoxidase; Butenafine Hydrochloride, a benzylamine derivative, is an antifungal which is used to control dermal fungal infections such as athletes foot and ring worm. MedChem Express HY-17396
      Butenafine hydrochloride is a synthetic benzylamine antifungal, works by inhibiting the synthesis of sterols by inhibiting squalene epoxidase.;IC50 Value: ;Target: Antifungal; squalene epoxidaseButenafine Hydrochloride, a benzylamine derivative, is an antifungal which is used to control dermal fungal infections such as athletes foot and ring worm. Butenafine Hydrochloride is squalene epoxidase inhibitor, inhibits the synthesis of ergosterol needed in fungal cell membranes. The drug has excellent penetration into the epidermis and a prolonged retention time following topical application, conferring residual therapeutic activity after treatment cessation. Butenafine possess anti-inflammatory activity too. Butenafine hydrochloride 1% cream is safe and effective for tinea corporis cruris and tinea manuum pedis. MedChem Express HY-17396
      Microbiology & Virology TargetMol T1217
      Squalene epoxidase TargetMol T1217

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

No predicted properties have been calculated for this compound.

Click to predict properties on the Chemicalize site


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