ChemSpider 2D Image | Avandia | C22H23N3O7S

Avandia

  • Molecular FormulaC22H23N3O7S
  • Average mass473.499 Da
  • Monoisotopic mass473.125671 Da
  • ChemSpider ID4444514

  • Double-bond stereo - Double-bond stereo

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

(±)-5-[[4-[2-(methyl-2-pyridinylamino)ethoxy]phenyl]methyl]-2,4-thiazolidinedione (Z)-2-butenedioate (1:1)
(2Z)-2-Butendisäure --5-(4-{2-[methyl(2-pyridinyl)amino]ethoxy}benzyl)-1,3-thiazolidin-2,4-dion (1:1) [German] [ACD/IUPAC Name]
(2Z)-But-2-endisäure--5-(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}benzyl)-1,3-thiazolidin-2,4-dion(1:1)
155141-29-0 [RN]
2,4-Thiazolidinedione, 5-[[4-[2-(methyl-2-pyridinylamino)ethoxy]phenyl]methyl]-, (2Z)-2-butenedioate (1:1) [ACD/Index Name]
5-(4-{2-[Methyl(2-pyridinyl)amino]ethoxy}benzyl)-1,3-thiazolidine-2,4-dione (2Z)-2-butenedioate (1:1) [ACD/IUPAC Name]
5-(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}benzyl)-1,3-thiazolidine-2,4-dione (2Z)-but-2-enedioate
5-(4-{2-[Methyl(pyridin-2-yl)amino]ethoxy}benzyl)-1,3-thiazolidine-2,4-dione (2Z)-but-2-enedioate (1:1)
5-{[4-({2-[methyl(pyridin-2-yl)amino]ethyl}oxy)phenyl]methyl}-1,3-thiazolidine-2,4-dione (2Z)-but-2-enedioate
Acide (2Z)-2-butènedioïque - 5-(4-{2-[méthyl(2-pyridinyl)amino]éthoxy}benzyl)-1,3-thiazolidine-2,4-dione (1:1) [French] [ACD/IUPAC Name]
More...

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

BRL-49653 [DBID]
D00596 [DBID]
NSC717764 [DBID]
SB-206846 [DBID]
SB-210232 [DBID]
  • References
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Target Organs:

      PPAR agonist TargetMol T1622

    • Bio Activity:

      Biochemicals & small molecules/Agonists & activators Hello Bio HB4140
      Cell Cycle/DNA Damage MedChem Express HY-14600
      Cell Cycle/DNA Damage; NF-KB; MedChem Express HY-14600
      Metabolism TargetMol T1622
      Potent and selective PPARγ agonist. Maleate salt. Potent insulin sensitizing agent which binds PPAR receptors to fat cells and making the cells more responsive to insulin. Ameliorates insulin resistance and shows antidiabetic, hypoglycemic and anti-inflammatory action. Also promotes mesenchymal stem cells (MSCs) adipocyte differentiation and enhances endogenous neural progenitor cells (NPCs) proliferation. Hello Bio HB4140
      Potent and selective PPARγ agonist; antidiabetic agent. Hello Bio HB4140
      PPAR MedChem Express HY-14600
      PPAR TargetMol T1622
      Receptors & Transporters/Nuclear hormone/PPAR/PPARγ Hello Bio HB4140
      Rosiglitazone maleate(BRL-49653C) is a high-affinity selective agonist of the peroxisome proliferator-activated receptor-?(PPAR?).; IC50 Value: ; Target: PPAR?; in vitro: In competition experiments, rosiglitazone (BRL-49653), a potent antihyperglycemic agent, binds with high affinity to sites in intact adipocytes (IC50 = 12, 4 and 9 nM for rat, 3T3-L1 and human adipocytes, respectively) [1]. MedChem Express HY-14600

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

No predicted properties have been calculated for this compound.

Click to predict properties on the Chemicalize site


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