ChemSpider 2D Image | Olmutinib | C26H26N6O2S

Olmutinib

  • Molecular FormulaC26H26N6O2S
  • Average mass486.589 Da
  • Monoisotopic mass486.183807 Da
  • ChemSpider ID45743494

More details:






Validated by Experts, Validated by Users, Non-Validated, Removed by Users

10093
1353550-13-6 [RN]
2-Propenamide, N-[3-[[2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]thieno[3,2-d]pyrimidin-4-yl]oxy]phenyl]- [ACD/Index Name]
CHL9B67L95
N-{3-[(2-{[4-(4-Methyl-1-piperazinyl)phenyl]amino}thieno[3,2-d]pyrimidin-4-yl)oxy]phenyl}acrylamid [German] [ACD/IUPAC Name]
N-{3-[(2-{[4-(4-Methyl-1-piperazinyl)phenyl]amino}thieno[3,2-d]pyrimidin-4-yl)oxy]phenyl}acrylamide [ACD/IUPAC Name]
N-{3-[(2-{[4-(4-Méthyl-1-pipérazinyl)phényl]amino}thiéno[3,2-d]pyrimidin-4-yl)oxy]phényl}acrylamide [French] [ACD/IUPAC Name]
olmutinib [French] [INN]
olmutinib [Spanish] [INN]
Olmutinib [INN]
More...

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

BI 1482694 [DBID]
HM61713 [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous
    • Bio Activity:

      Btk MedChem Express HY-19730
      EGFR MedChem Express HY-19730
      JAK/STAT Signaling; Protein Tyrosine Kinase/RTK; MedChem Express HY-19730
      Olmutinib (HM71224) is a potent small molecule inhibitor of Bruton's tyrosine kinase (BTK). MedChem Express HY-19730
      Olmutinib is an EGFR tyrosine kinase inhibitor.;Target: EGFROlmutinib is an Epidermal growth factor receptor (EGFR) antagonist. MedChem Express HY-19730
      Protein Tyrosine Kinase/RTK MedChem Express HY-19730

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module

Density: 1.3±0.1 g/cm3
Boiling Point:
Vapour Pressure:
Enthalpy of Vaporization:
Flash Point:
Index of Refraction: 1.706
Molar Refractivity: 141.6±0.3 cm3
#H bond acceptors: 8
#H bond donors: 2
#Freely Rotating Bonds: 7
#Rule of 5 Violations: 0
ACD/LogP: 4.95
ACD/LogD (pH 5.5): 1.75
ACD/BCF (pH 5.5): 3.92
ACD/KOC (pH 5.5): 23.17
ACD/LogD (pH 7.4): 3.47
ACD/BCF (pH 7.4): 204.07
ACD/KOC (pH 7.4): 1205.58
Polar Surface Area: 111 Å2
Polarizability: 56.1±0.5 10-24cm3
Surface Tension: 67.0±3.0 dyne/cm
Molar Volume: 364.1±3.0 cm3

Click to predict properties on the Chemicalize site





Feedback Form