ChemSpider 2D Image | Ceftazidime | C22H22N6O7S2

Ceftazidime

  • Molecular FormulaC22H22N6O7S2
  • Average mass546.576 Da
  • Monoisotopic mass546.099121 Da
  • ChemSpider ID4587145
  • Double-bond stereo - Double-bond stereo

    defined stereocentres - 2 of 2 defined stereocentres


More details:



Featured data source



Validated by Experts, Validated by Users, Non-Validated, Removed by Users

(6R(6a,7b(Z)))-1-((7-(((2-Amino-4-thiazolyl)((1-carboxy-1-methylethoxy)imino)acetyl)amino)-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl)methyl)pyridinium hydroxide Inner Salt
(6R,7R)-7-({(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-[(1-carboxy-1-methylethoxy)imino]acetyl}amino)-8-oxo-3-(pyridinium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-en-2-carboxylat [German]
(6R,7R)-7-({(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(1-carboxy-1-methylethoxy)imino]acetyl}amino)-8-oxo-3-(pyridinium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
(6R,7R)-7-({(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(1-carboxy-1-méthyléthoxy)imino]acétyl}amino)-8-oxo-3-(pyridinium-1-ylméthyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ène-2-carboxylate [French]
(6R,7R)-7-[(Z)-2-(Aminothiazol-4-yl)-2-(2-carboxypropoxyimino)acetamido]-3-(1-pyridiniummethyl)ceph-3-em-4-carboxylate
(6R,7R)-7-{[(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(1-carboxy-1-methylethyl)oxy]imino}acetyl]amino}-8-oxo-3-(pyridinium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
(6R,7R)-7-{[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-{[(2-carboxy-2-propanyl)oxy]imino}acetyl]amino}-8-oxo-3-(1-pyridiniumylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-en-2-carboxylat [German] [ACD/IUPAC Name]
(6R,7R)-7-{[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-{[(2-carboxy-2-propanyl)oxy]imino}acetyl]amino}-8-oxo-3-(1-pyridiniumylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate [ACD/IUPAC Name]
(6R,7R)-7-{[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-{[(2-carboxy-2-propanyl)oxy]imino}acétyl]amino}-8-oxo-3-(1-pyridiniumylméthyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ène-2-carboxylate [French] [ACD/IUPAC Name]
(6R,7R)-7-{[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-8-oxo-3-(pyridinium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
More...

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

LY 139381 [DBID]
BRN 4344904 [DBID]
C06889 [DBID]
CCRIS 937 [DBID]
GR 20263 [DBID]
SN 401 [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous
    • Safety:

      GHS07 Biosynth Q-200813
      H302; H312; H315; H319; H332; H335 Biosynth Q-200813
      J01DD02 Wikidata Q808845
      P261; P280; P302+P352; P304+P340; P305+P351+P338; P312 Biosynth Q-200813
      Warning Biosynth Q-200813
      Xn Abblis Chemicals AB1009357
    • Target Organs:

      Antibiotic TargetMol T1305
    • Chemical Class:

      A cephalosporin bearing pyridinium-1-ylmethyl and {[(2<stereo>Z</stereo>)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetamido groups at positions 3 and 7, respectively, of the c ephem skeleton. ChEBI CHEBI:3508
    • Therapeutical Effect:

      Anti-Bacterial Agents Sean Ekins
    • Bio Activity:

      Antibacterial MedChem Express HY-B0593
      Anti-infection MedChem Express HY-B0593
      Anti-infection; MedChem Express HY-B0593
      Ceftazidime(GR20263) is an antibiotic useful for the treatment of a number of bacterial infections. MedChem Express
      Ceftazidime(GR20263) is an antibiotic useful for the treatment of a number of bacterial infections.; Target: Antibacterial; Ceftazidime is an antibiotic useful for the treatment of a number of bacterial infections. MedChem Express HY-B0593
      Ceftazidime(GR20263) is an antibiotic useful for the treatment of a number of bacterial infections.;Target: AntibacterialCeftazidime is an antibiotic useful for the treatment of a number of bacterial infections. It is a third-generation cephalosporin. As with all antibiotics, ceftazidime is not used to treat viral infections. Cephalosporins have activity against Gram-positive and Gram-negative bacteria. The balance of activity tips toward Gram-positive organisms for earlier generations; later generations of cephalosporins have more Gram-negative coverage. Ceftazidime is one of the few in this class with activity against Pseudomonas. It is not active against Methicillin-resistant Staphylococcus aureus. From Wikipedia. MedChem Express HY-B0593
      Microbiology & Virology TargetMol T1305
      Peptidoglycan synthase;PBPs TargetMol T1305

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module

Density:
Boiling Point:
Vapour Pressure:
Enthalpy of Vaporization:
Flash Point:
Index of Refraction:
Molar Refractivity:
#H bond acceptors: 13
#H bond donors: 5
#Freely Rotating Bonds: 9
#Rule of 5 Violations: 3
ACD/LogP: -2.84
ACD/LogD (pH 5.5): -3.15
ACD/BCF (pH 5.5): 1.00
ACD/KOC (pH 5.5): 1.00
ACD/LogD (pH 7.4): -3.21
ACD/BCF (pH 7.4): 1.00
ACD/KOC (pH 7.4): 1.00
Polar Surface Area: 245 Å2
Polarizability:
Surface Tension:
Molar Volume:

Click to predict properties on the Chemicalize site





Feedback Form