ChemSpider 2D Image | Riluzole HCl | C8H6ClF3N2OS

Riluzole HCl

  • Molecular FormulaC8H6ClF3N2OS
  • Average mass270.659 Da
  • Monoisotopic mass269.984131 Da
  • ChemSpider ID4925582

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

2-Benzothiazolamine, 6-(trifluoromethoxy)-, hydrochloride (1:1) [ACD/Index Name]
6-(Trifluormethoxy)-1,3-benzothiazol-2-aminhydrochlorid (1:1) [German] [ACD/IUPAC Name]
6-(Trifluoromethoxy)-1,3-benzothiazol-2-amine hydrochloride (1:1) [ACD/IUPAC Name]
6-(Trifluorométhoxy)-1,3-benzothiazol-2-amine, chlorhydrate (1:1) [French] [ACD/IUPAC Name]
850608-87-6 [RN]
Riluzole (hydrochloride)
Riluzole HCl
[850608-87-6] [RN]
1744-22-5 [RN]
2-Amino-6-trifluoromethoxybenzothiazole hydrochloride
More...

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

Prestwick_644 [DBID]
UN 2811 [DBID]
UN2811 [DBID]
  • Experimental Physico-chemical Properties

    • Experimental Solubility:

      Soluble in DMSO (100mM, gentle warming) and in water (10mM, gentle warming) Hello Bio HB0548
      Soluble to 100 mM in DMSO and to 10 mM in water with gentle warming Tocris Bioscience 0768, 768
      Soluble to 100 mM in DMSO and to 50 mM in water Tocris Bioscience 0768
  • Miscellaneous

    • Bio Activity:

      <p>Na<sup>+</sup> channel blocker. Increases glutamate uptake and inhibits glutamate release and also inhibits GABA uptake. Non-competitive NMDA receptor and Protein kinase C (PKC) inhibitor. Also a TREK-1 K2P channel activator. Shows neuroprotective, anxiolytic, anticonvulsant and anesthetic actions. Shows actions against motorneuron disease.</p> Hello Bio HB0548
      GABA Transporters Tocris Bioscience 768
      GABA uptake inhibitor. Also glutamate release inhibitor Tocris Bioscience 768
      Glutamate (Ionotropic) Receptors Tocris Bioscience 768
      Glutamate release inhibitor/GABA uptake inhibitor Tocris Bioscience 0768, 768
      Ion Channels Tocris Bioscience 768
      Ion channels/Ligand-gated ion channel/Ionotropic glutamate receptors/Miscellaneous Hello Bio HB0548
      Ion channels/Voltage-gated ion channel/Sodium Channels Hello Bio HB0548
      Ligand-gated Ion Channels Tocris Bioscience 768
      Na<sup>+</sup> channel blocker / glutamate inhibitor Hello Bio HB0548
      Na<sup>+</sup> channel blocker. Increases glutamate uptake and inhibits glutamate release. Also inhibits GABA uptake. Non-competitive NMDA receptor and Protein kinase C (PKC) inhibitor. Shows neuroprotective, anxiolytic, anticonvulsant and anesthetic actions. Shows actions against motorneuron disease. Hello Bio HB0548
      Neurotransmitter Transporters Tocris Bioscience 768
      Novel psychotropic agent with anticonvulsant, hypnotic, anxiolytic, anti-ischemic and anesthetic properties. Inhibits glutamate release from presynaptic terminals and increases Na+-dependent glutamate uptake in rat cortical synaptosomes. Blocks voltage-dependent Na+ channels and inhibits GABA uptake by striatal synaptosomes; neuroprotective. Tocris Bioscience 0768
      Psychotropic agent with anticonvulsant, hypnotic, anxiolytic, anti-ischemic and anesthetic properties. Inhibits glutamate release from presynaptic terminals and increases Na+-dependent glutamate uptake in rat cortical synaptosomes. Blocks voltage-dependent Na+ channels and inhibits GABA uptake by striatal synaptosomes; neuroprotective. Tocris Bioscience 768
      Receptors & Transporters/G protein coupled receptors/Metabotropic glutamate/Miscellaneous Hello Bio HB0548
      Transporters Tocris Bioscience 768
      Type/Biochemicals & small molecules/Antagonists & inhibitors Hello Bio HB0548

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

No predicted properties have been calculated for this compound.

Click to predict properties on the Chemicalize site


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