ChemSpider 2D Image | Pravastatin sodium | C23H35NaO7

Pravastatin sodium

  • Molecular FormulaC23H35NaO7
  • Average mass446.510 Da
  • Monoisotopic mass446.228058 Da
  • ChemSpider ID49400

  • Charge - Charge

    defined stereocentres - 8 of 8 defined stereocentres

More details:

Featured data source
The Merck Index Online

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

(3R,5R)-3,5-Dihydroxy-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-méthyl-8-{[(2S)-2-méthylbutanoyl]oxy}-1,2,6,7,8,8a-hexahydro-1-naphtalényl]heptanoate de sodium [French] [ACD/IUPAC Name]
(3R,5R)-3,5-dihydroxy-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-méthyl-8-{[(2S)-2-méthylbutanoyl]oxy}-1,2,6,7,8,8a-hexahydronaphtalén-1-yl]heptanoate de sodium [French]
(βR, δR,1S,2S,6S,8S,8aR)-1,2,6,7,8,8a-Hexahydro-β, δ,6-trihydroxy-2-methyl-8[(2S)-2-methyl-1-oxobutoxyl]-1-naphthaleneheptanoic acid sodium hydrate
[1S-[1a(bS*,dS*),2a,6a,8b(R*),8aa]]-1,2,6,7,8,8a-Hexahydro-b,d,6-trihydroxy-2-methyl-8-(2-methyl-1-oxobutoxy)-1-naphthaleneheptanoic Acid Monosodium Salt
1-Naphthaleneheptanoic acid, 1,2,6,7,8,8a-hexahydro-β,δ,6-trihydroxy-2-methyl-8-[(2S)-2-methyl-1-oxobutoxy]-, sodium salt, (βR,δR,1S,2S,6S,8S,8aR)- (1:1) [ACD/Index Name]
1-naphthaleneheptanoic acid, 1,2,6,7,8,8a-hexahydro-β,δ,6-trihydroxy-2-methyl-8-[[(2S)-2-methyl-1-oxobutyl]oxy]-, monosodium salt, (βR,δR,1S,2S,6S,8S,8aR)-
3b-Hydroxycompactin Sodium Salt
3M8608UQ61
81131-70-6 [RN]
Eptastatin sodium salt hydrate
More...

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

CHEBI:8361 [DBID]
CS 514 [DBID]
DRG 0319 [DBID]
CS-514 [DBID]
D00893 [DBID]
DRG-0319 [DBID]
SQ 31000 [DBID]
SQ-31000 [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Chemical Class:

      An organic sodium salt that is the sodium salt of pravastatin. A reversible inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA), it is used for lowering cholesterol and preventing cardiovascu lar disease. It is one of the lower potency statins, but has the advantage of fewer side effects compared with lovastatin and simvastatin. ChEBI https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:8361, CHEBI:8361

    • Bio Activity:

      Enzymes Tocris Bioscience 2318
      HMG-CoA Reductase Tocris Bioscience 2318
      HMG-CoA Reductase (HMGCR) MedChem Express HY-B0165A
      HMG-CoA reductase inhibitor Tocris Bioscience 2318
      Metabolism/Protease MedChem Express HY-B0165A
      Metabolism/Protease; MedChem Express HY-B0165A
      Pravastatin sodium is an HMG-CoA reductase inhibitor against sterol synthesis with IC50 of 5.6 ?M.; Target: HMG-CoA reductase; Pravastatin (marketed as Pravachol or Selektine) is a member of the drug class of statins, used in combination with diet, exercise, and weight-loss for lowering cholesterol and preventing cardiovascular disease.; Pravastatin is primarily used for the treatment of dyslipidemia and the prevention of cardiovascular disease. MedChem Express HY-B0165A
      Reductases Tocris Bioscience 2318
      Water-soluble, competitive inhibitor of 3-hydroxy-3-methyl coenzyme A (HMG-CoA) reductase. Potently blocks cholesterol synthesis in vivo (Ki~ 1 nM) and displays cardioprotective properties. Tocris Bioscience 2318

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

No predicted properties have been calculated for this compound.

Click to predict properties on the Chemicalize site


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