ChemSpider 2D Image | Cilastatin Sodium | C16H25N2NaO5S

Cilastatin Sodium

  • Molecular FormulaC16H25N2NaO5S
  • Average mass Da
  • Monoisotopic mass Da
  • ChemSpider ID5293165

  • Charge - Charge

    Double-bond stereo - Double-bond stereo

    defined stereocentres - 2 of 2 defined stereocentres

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

(2R)-2-amino-3-{[(5Z)-6-carboxy-6-({[(1S)-2,2-diméthylcyclopropyl]carbonyl}amino)hex-5-én-1-yl]sulfanyl}propanoate de sodium
(2Z)-7-{[(2R)-2-Amino-2-carboxyéthyl]sulfanyl}-2-({[(1S)-2,2-diméthylcyclopropyl]carbonyl}amino)-2-hepténoate de sodium [French] [ACD/IUPAC Name]
[R-[R*,S*(Z)]]-7-[(2-Amino-2-carboxyethyl)thio]-2-[[(2,2-dimethylcyclopropyl)carbonyl]amino]-2-heptenoic Acid Monosodium Salt
279-694-4 [EINECS]
2-heptenoic acid, 7-[[(2R)-2-amino-2-carboxyethyl]thio]-2-[[[(1S)-2,2-dimethylcyclopropyl]carbonyl]amino]-, monosodium salt, (2Z)-
2-Heptenoic acid, 7-[[(2R)-2-amino-2-carboxyethyl]thio]-2-[[[(1S)-2,2-dimethylcyclopropyl]carbonyl]amino]-, sodium salt, (2Z)- (1:1) [ACD/Index Name]
81129-83-1 [RN]
Cilastatin Sodium
Cilastatin sodium salt
Natrium-(2R)-2-amino-3-{[(5Z)-6-carboxy-6-({[(1S)-2,2-dimethylcyclopropyl]carbonyl}amino)hex-5-en-1-yl]sulfanyl}propanoat
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Validated by Experts, Validated by Users, Non-Validated, Removed by Users

5428WXZ74M [DBID]
L 642957 [DBID]
8179743 [DBID]
L-642957 [DBID]
MK-791 [DBID]
UNII-5428WXZ74M [DBID]
  • Miscellaneous

    • Chemical Class:

      The monosodium salt of cilastatin. It is an inhibitor of dehydropeptidase I (membrane dipeptidase, 3.4.13.19), an enzyme found in the brush border of renal tubes and responsible for degrading the anti biotic imipenem. Cilastatin sodium is therefore administered with imipenem to prolong the antibacterial effect of the latter by preventing its renal metabolism to microbiologically inactive and potent ially nephrotoxic products. ChEBI https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:59511, CHEBI:59511

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

No predicted properties have been calculated for this compound.

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