ChemSpider 2D Image | Vilazodone hydrochloride | C26H28ClN5O2

Vilazodone hydrochloride

  • Molecular FormulaC26H28ClN5O2
  • Average mass477.986 Da
  • Monoisotopic mass477.193146 Da
  • ChemSpider ID5293517

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

163521-08-2 [RN]
200-659-6 [EINECS]
2-Benzofurancarboxamide, 5-[4-[4-(5-cyano-1H-indol-3-yl)butyl]-1-piperazinyl]-, hydrochloride (1:1) [ACD/Index Name]
5-[4-[4-(5-Cyano-1H-indol-3-yl)butyl]-1-piperazinyl]- 2-benzofurancarboxamide hydrochloride
5-{4-[4-(5-Cyan-1H-indol-3-yl)butyl]-1-piperazinyl}-1-benzofuran-2-carboxamidhydrochlorid (1:1) [German] [ACD/IUPAC Name]
5-{4-[4-(5-Cyano-1H-indol-3-yl)butyl]-1-piperazinyl}-1-benzofuran-2-carboxamide hydrochloride (1:1) [ACD/IUPAC Name]
5-{4-[4-(5-Cyano-1H-indol-3-yl)butyl]-1-pipérazinyl}-1-benzofurane-2-carboxamide, chlorhydrate (1:1) [French] [ACD/IUPAC Name]
EMD 68843
MFCD00940014 [MDL number]
SB 659746A.
More...

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

EMD 68 843 [DBID]
SB659746-A [DBID]
EMD-68843 [DBID]
SB 659746A [DBID]
SB-659746A [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Chemical Class:

      A hydrochloride obtained by reaction of vilazodone with one equivalent of hydrochloric acid. Used for the treatment of major depressive disorder. ChEBI https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:70705, CHEBI:70705

    • Bio Activity:

      5-HT Receptor SSRIs MedChem Express HY-14261
      5-HT Receptors Tocris Bioscience 6202
      5-HT1 Receptors Tocris Bioscience 6202
      7-TM Receptors Tocris Bioscience 6202
      GPCR/G protein; Neuronal Signaling; MedChem Express HY-14261
      Potent 5-HT1A partial agonist and serotonin-selective reuptake inhibitor (SSRI) (IC50 values are 0.2 and 0.5 nM respectively). Antidepressant. Tocris Bioscience 6202
      Potent 5-HT1A partial agonist and SSRI; antidepressant Tocris Bioscience 6202
      Vilazodone Hcl (EMD 68843; SB 659746A) is a combined serotonin specific reuptake inhibitor (SSRI) and 5-HT1A receptor partial agonist currently under clinical evaluation for the treatment of major dep ression. MedChem Express
      Vilazodone Hcl (EMD 68843; SB 659746A) is a combined serotonin specific reuptake inhibitor (SSRI) and 5-HT1A receptor partial agonist currently under clinical evaluation for the treatment of major depression.;IC50 value:;Target: SSRI; 5-HT1AVilazodone represents another option for the treatment of MDD. Vilazodone appears to have a favourable weight-gain profile based on short-term studies. Sexual side-effects were not consistently demonstrated when assessed using clinical rating scales but spontaneously reported AEs related to sexual functioning were observed. Additional controlled data regarding long-term efficacy and effectiveness will help characterise this new agent when used in maintenance treatment. MedChem Express HY-14261

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

No predicted properties have been calculated for this compound.

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