ChemSpider 2D Image | Pilocarpine hydrochloride | C11H17ClN2O2

Pilocarpine hydrochloride

  • Molecular FormulaC11H17ClN2O2
  • Average mass244.718 Da
  • Monoisotopic mass244.097855 Da
  • ChemSpider ID5698

  • defined stereocentres - 2 of 2 defined stereocentres

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

(+)-Pilocarpine (hydrochloride)
(3S,4R)-3-Ethyl-4-[(1-methyl-1H-imidazol-5-yl)methyl]dihydro-2(3H)-furanone hydrochloride (1:1) [ACD/IUPAC Name]
(3S,4R)-3-Éthyl-4-[(1-méthyl-1H-imidazol-5-yl)méthyl]dihydro-2(3H)-furanone, chlorhydrate (1:1) [French] [ACD/IUPAC Name]
(3S,4R)-3-Ethyl-4-[(1-methyl-1H-imidazol-5-yl)methyl]dihydro-2(3H)-furanonhydrochlorid (1:1) [German] [ACD/IUPAC Name]
(3S,4R)-3-éthyl-4-[(1-méthyl-1H-imidazol-5-yl)méthyl]dihydrofuran-2(3H)-one chlorhydrate
(3S,4R)-3-ethyl-4-[(1-methyl-1H-imidazol-5-yl)methyl]dihydrofuran-2(3H)-one hydrochloride
(3S,4R)-3-Ethyl-4-[(1-methyl-1H-imidazol-5-yl)methyl]dihydrofuran-2(3H)-one hydrochloride (1:1)
(3S,4R)-3-Ethyl-4-[(1-methyl-1H-imidazol-5-yl)methyl]dihydrofuran-2(3H)-onhydrochlorid
(3S,4R)-3-ethyl-4-[(1-methyl-1H-imidazol-5-yl)methyl]oxolan-2-one hydrochloride
(3S,4R)-4,5-Dihydro-3-ethyl-4-(1-methyl-1H-imidazol-5-ylmethyl)-2(3H)-furanone hydrochloride
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Validated by Experts, Validated by Users, Non-Validated, Removed by Users

4034491 [DBID]
AI3-61859 [DBID]
D02200 [DBID]
EU-0100950 [DBID]
MLS000069454 [DBID]
NSC 5746 [DBID]
NSC5746 [DBID]
P0472_SIGMA [DBID]
P6503_SIGMA [DBID]
SMR000059053 [DBID]
More...
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Safety:

      25-45 Alfa Aesar B21410
      26/28 Alfa Aesar B21410
      6.1 Alfa Aesar B21410
      Danger Alfa Aesar B21410
      DANGER: POISON, causes CNS injury Alfa Aesar B21410
      H300-H330 Alfa Aesar B21410
      P260-P301+P310-P304+P340-P320-P330-P405-P501a Alfa Aesar B21410

    • Chemical Class:

      The hydrochloride salt of (+)-pilocarpine, a medication used to treat increased pressure inside the eye and dry mouth. ChEBI CHEBI:141029

    • Bio Activity:

      7-TM Receptors Tocris Bioscience 694
      Acetylcholine (Muscarinic) Receptors Tocris Bioscience 694
      Acetylcholine Muscarinic Receptors Tocris Bioscience 694
      GPCR/G protein MedChem Express HY-B0726
      GPCR/G protein; Neuronal Signaling; MedChem Express HY-B0726
      mAChR MedChem Express HY-B0726
      Muscarinic agonist Tocris Bioscience 0694, 694
      Muscarinic agonist. Tocris Bioscience 0694, 694
      Non-selective Muscarinics Tocris Bioscience 694
      Pilocarpine HCl is a nonselective muscarinic acetylcholine receptor agonist used to produce an experimental model of epilepsy. MedChem Express
      Pilocarpine HCl is a nonselective muscarinic acetylcholine receptor agonist used to produce an experimental model of epilepsy.; Target: mAChR; Pilocarpine is a parasympathomimetic alkaloid obtained from the leaves of tropical American shrubs from the genus Pilocarpus. MedChem Express HY-B0726
      Pilocarpine HCl is a nonselective muscarinic acetylcholine receptor agonist used to produce an experimental model of epilepsy.;Target: mAChRPilocarpine is a parasympathomimetic alkaloid obtained from the leaves of tropical American shrubs from the genus Pilocarpus. It is a non-selective muscarinic receptor agonist in the parasympathetic nervous system, which acts therapeutically at themuscarinic acetylcholine receptor M3 due to its topical application, e.g., in glaucoma and xerostomia. Pilocarpine acts on a subtype of muscarinic receptor (M3) found on the iris sphincter muscle, causing the muscle to contract and engage in miosis [1]. Pilocarpine also acts on the ciliary muscle and causes it to contract. When the ciliary muscle contracts, it opens the trabecular meshwork through increased tension on the scleral spur. This action facilitates the rate that aqueous humorleaves the eye to decrease intraocular pressure. In ophthalmology, pilocarpine is also used to reduce the possibility MedChem Express HY-B0726

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

No predicted properties have been calculated for this compound.

Click to predict properties on the Chemicalize site


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