ChemSpider 2D Image | VU0409551 | C20H17FN2O3

VU0409551

  • Molecular FormulaC20H17FN2O3
  • Average mass352.359 Da
  • Monoisotopic mass352.122314 Da
  • ChemSpider ID57427165

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

(4-Fluorophenyl)[2-(phenoxymethyl)-6,7-dihydro[1,3]oxazolo[5,4-c]pyridin-5(4H)-yl]methanone [ACD/IUPAC Name]
(4-Fluorophényl)[2-(phénoxyméthyl)-6,7-dihydro[1,3]oxazolo[5,4-c]pyridin-5(4H)-yl]méthanone [French] [ACD/IUPAC Name]
(4-Fluorphenyl)[2-(phenoxymethyl)-6,7-dihydro[1,3]oxazolo[5,4-c]pyridin-5(4H)-yl]methanon [German] [ACD/IUPAC Name]
1363281-27-9 [RN]
Methanone, [6,7-dihydro-2-(phenoxymethyl)oxazolo[5,4-c]pyridin-5(4H)-yl](4-fluorophenyl)- [ACD/Index Name]
VU0409551
(4-fluorophenyl)(2-(phenoxymethyl)-6,7-dihydrooxazolo[5,4-c]pyridin-5(4H)-yl)methanone
[1363281-27-9] [RN]
[6,7-dihydro-2-(phenoxymethyl)oxazolo[5,4-c]pyridin-5(4H)-yl](4-fluorophenyl)-methanone
[6,7-Dihydro-2-(phenoxymethyl)oxazolo[5,4-c]pyridin-5(4H)-yl](4-fluorophenyl)methanone
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Validated by Experts, Validated by Users, Non-Validated, Removed by Users

CCRIS 4693 [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Bio Activity:

      7-TM Receptors Tocris Bioscience 5693
      Glutamate (Metabotropic) Group I Receptors Tocris Bioscience 5693
      Glutamate (Metabotropic) Receptors Tocris Bioscience 5693
      Selective mGlu5 positive allosteric modulator (EC50 = 260 nM). Selective for mGlu5 over other mGluR subtypes, as well as 66 other receptors and ion channels. Selectively potentiates mGlu5 signaling via G?q. Exhibits wake-promoting, antipsychotic-like and cognition-enhancing effects in animal models. Brain penetrant and orally available. Tocris Bioscience 5693
      Selective mGlu5 positive allosteric modulator (EC50 = 260 nM). Selective for mGlu5 over other mGluR subtypes, as well as 66 other receptors and ion channels. Selectively potentiates mGlu5 signaling via Galphaq. Exhibits wake-promoting, antipsychotic-like and cognition-enhancing effects in animal models. Brain penetrant and orally available. Tocris Bioscience 5693
      Selective mGlu5 positive allosteric modulator; brain penetrant and orally bioavailable Tocris Bioscience 5693

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

Density: 1.3±0.1 g/cm3
Boiling Point: 545.8±50.0 °C at 760 mmHg
Vapour Pressure: 0.0±1.5 mmHg at 25°C
Enthalpy of Vaporization: 82.5±3.0 kJ/mol
Flash Point: 283.9±30.1 °C
Index of Refraction: 1.609
Molar Refractivity: 93.2±0.3 cm3
#H bond acceptors: 5
#H bond donors: 0
#Freely Rotating Bonds: 4
#Rule of 5 Violations: 0
ACD/LogP: 2.11
ACD/LogD (pH 5.5): 3.30
ACD/BCF (pH 5.5): 188.87
ACD/KOC (pH 5.5): 1482.07
ACD/LogD (pH 7.4): 3.30
ACD/BCF (pH 7.4): 188.88
ACD/KOC (pH 7.4): 1482.18
Polar Surface Area: 56 Å2
Polarizability: 36.9±0.5 10-24cm3
Surface Tension: 53.6±3.0 dyne/cm
Molar Volume: 269.3±3.0 cm3

Click to predict properties on the Chemicalize site


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