ChemSpider 2D Image | ASP9521 | C19H26N2O3

ASP9521

  • Molecular FormulaC19H26N2O3
  • Average mass330.421 Da
  • Monoisotopic mass330.194336 Da
  • ChemSpider ID57579727

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

[4-(2-Hydroxy-2-methylpropyl)-1-piperidinyl](5-methoxy-1H-indol-2-yl)methanon [German] [ACD/IUPAC Name]
[4-(2-Hydroxy-2-methylpropyl)-1-piperidinyl](5-methoxy-1H-indol-2-yl)methanone [ACD/IUPAC Name]
[4-(2-Hydroxy-2-méthylpropyl)-1-pipéridinyl](5-méthoxy-1H-indol-2-yl)méthanone [French] [ACD/IUPAC Name]
1-[1-(5-methoxy-1H-indole-2-carbonyl)piperidin-4-yl]-2-methylpropan-2-ol
1126084-37-4 [RN]
ASP9521
Methanone, [4-(2-hydroxy-2-methylpropyl)-1-piperidinyl](5-methoxy-1H-indol-2-yl)- [ACD/Index Name]
[1126084-37-4] [RN]
[4-(2-hydroxy-2-methylpropyl)-1-piperidinyl](5-methoxy-1H-indol-2-yl)-methanone
ASP 9521
More...
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Bio Activity:

      Dehydrogenases Tocris Bioscience 6084
      Enzymes Tocris Bioscience 6084
      Other Dehydrogenases Tocris Bioscience 6084
      Potent 17beta-hydroxysteroid dehydrogenase type 5 inhibitor (IC50 = 11 - 49 nM). Suppresses androstenedione-dependent protein-specific antigen (PSA) production and cell proliferation in LNCaP cells in vitro. Orally bioavailable. Tocris Bioscience 6084
      Potent 17beta-hydroxysteroid dehydrogenase type 5 inhibitor;orally bioavailable Tocris Bioscience 6084

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

Density: 1.2±0.1 g/cm3
Boiling Point: 543.9±30.0 °C at 760 mmHg
Vapour Pressure: 0.0±1.5 mmHg at 25°C
Enthalpy of Vaporization: 86.5±3.0 kJ/mol
Flash Point: 282.7±24.6 °C
Index of Refraction: 1.599
Molar Refractivity: 95.3±0.3 cm3
#H bond acceptors: 5
#H bond donors: 2
#Freely Rotating Bonds: 4
#Rule of 5 Violations: 0
ACD/LogP: 0.62
ACD/LogD (pH 5.5): 2.22
ACD/BCF (pH 5.5): 28.75
ACD/KOC (pH 5.5): 385.23
ACD/LogD (pH 7.4): 2.22
ACD/BCF (pH 7.4): 28.75
ACD/KOC (pH 7.4): 385.23
Polar Surface Area: 66 Å2
Polarizability: 37.8±0.5 10-24cm3
Surface Tension: 50.1±3.0 dyne/cm
Molar Volume: 279.1±3.0 cm3

Click to predict properties on the Chemicalize site


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