ChemSpider 2D Image | AM2394 | C22H25N5O4

AM2394

  • Molecular FormulaC22H25N5O4
  • Average mass423.465 Da
  • Monoisotopic mass423.190643 Da
  • ChemSpider ID58830974

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

1-[6'-(2-hydroxy-2-methylpropoxy)-4-[(5-methylpyridin-3-yl)oxy]-[3,3'-bipyridin]-6-yl]-3-methylurea
1-{6'-(2-Hydroxy-2-methylpropoxy)-4-[(5-methyl-3-pyridinyl)oxy]-3,3'-bipyridin-6-yl}-3-methylharnstoff [German] [ACD/IUPAC Name]
1-{6'-(2-Hydroxy-2-methylpropoxy)-4-[(5-methyl-3-pyridinyl)oxy]-3,3'-bipyridin-6-yl}-3-methylurea [ACD/IUPAC Name]
1-{6'-(2-Hydroxy-2-méthylpropoxy)-4-[(5-méthyl-3-pyridinyl)oxy]-3,3'-bipyridin-6-yl}-3-méthylurée [French] [ACD/IUPAC Name]
1442684-77-6 [RN]
AM2394
Urea, N-[6'-(2-hydroxy-2-methylpropoxy)-4-[(5-methyl-3-pyridinyl)oxy][3,3'-bipyridin]-6-yl]-N'-methyl- [ACD/Index Name]
[1442684-77-6] [RN]
1-(6'-(2-Hydroxy-2-methylpropoxy)-4-((5-methylpyridin-3-yl)oxy)-[3,3'-bipyridin]-6-yl)-3-methylurea
AM 2394
More...
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Bio Activity:

      Enzymes Tocris Bioscience 6034
      Hexokinases Tocris Bioscience 6034
      Kinases Tocris Bioscience 6034
      Potent glucokinase activator (EC50 = 60 nM). Orally bioavailable. Reduces plasma glucose levels in an oral glucose tolerance test in ob/ob mice. Tocris Bioscience 6034
      Potent glucokinase activator; orally bioavailable Tocris Bioscience 6034

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

Density: 1.3±0.1 g/cm3
Boiling Point: 588.8±50.0 °C at 760 mmHg
Vapour Pressure: 0.0±1.7 mmHg at 25°C
Enthalpy of Vaporization: 92.4±3.0 kJ/mol
Flash Point: 309.9±30.1 °C
Index of Refraction: 1.613
Molar Refractivity: 116.3±0.3 cm3
#H bond acceptors: 9
#H bond donors: 3
#Freely Rotating Bonds: 7
#Rule of 5 Violations: 0
ACD/LogP: 3.00
ACD/LogD (pH 5.5): 2.62
ACD/BCF (pH 5.5): 57.13
ACD/KOC (pH 5.5): 621.74
ACD/LogD (pH 7.4): 2.64
ACD/BCF (pH 7.4): 59.72
ACD/KOC (pH 7.4): 649.98
Polar Surface Area: 118 Å2
Polarizability: 46.1±0.5 10-24cm3
Surface Tension: 55.3±3.0 dyne/cm
Molar Volume: 334.2±3.0 cm3

Click to predict properties on the Chemicalize site


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