ChemSpider 2D Image | Lercanidipine | C36H41N3O6

Lercanidipine

  • Molecular FormulaC36H41N3O6
  • Average mass611.727 Da
  • Monoisotopic mass611.299561 Da
  • ChemSpider ID59276

More details:



Featured data source



Validated by Experts, Validated by Users, Non-Validated, Removed by Users

(±)-2-((3,3-diphenylpropyl)(methyl)amino)-1,1-dimethylethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 2-[(3,3-Diphenylpropyl)methylamino]-1,1-dimethylethyl Methyl Ester
1-[(3,3-Diphenylpropyl)(methyl)amino]-2-methyl-2-propanyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydro-3,5-pyridinedicarboxylate [ACD/IUPAC Name]
1-[(3,3-Diphenylpropyl)(methyl)amino]-2-methyl-2-propanyl-methyl-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydro-3,5-pyridindicarboxylat [German] [ACD/IUPAC Name]
1-[(3,3-diphenylpropyl)(methyl)amino]-2-methylpropan-2-yl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
100427-26-7 [RN]
2,6-Diméthyl-4-(3-nitrophényl)-1,4-dihydro-3,5-pyridinedicarboxylate de 1-[(3,3-diphénylpropyl)(méthyl)amino]-2-méthyl-2-propanyle et de méthyle [French] [ACD/IUPAC Name]
3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethyl methyl ester [ACD/Index Name]
6971
Lercanidipine [INN] [Wiki]
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Validated by Experts, Validated by Users, Non-Validated, Removed by Users

J8GF8BXI8S [DBID]
PubChem Substance ID 329831176 [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous
    • Safety:

      C08CA13 Wikidata Q410492
    • Bio Activity:

      Calcium Channel MedChem Express HY-B0612
      Lercanidipine is a calcium channel blocker of the dihydropyridine class. MedChem Express
      Lercanidipine is a calcium channel blocker of the dihydropyridine class.; Target: Calcium Channel; Lercanidipine is a calcium channel blocker of the dihydropyridine class, which works by relaxing and opening the blood vessels allowing the blood to circulate more freely around the body. MedChem Express HY-B0612
      Lercanidipine is a calcium channel blocker of the dihydropyridine class.;Target: Calcium ChannelLercanidipine is a calcium channel blocker of the dihydropyridine class, which works by relaxing and opening the blood vessels allowing the blood to circulate more freely around the body. Lercanidipine was effective and well-tolerated in patients with mild-to-moderate hypertension in the daily practice. The effectiveness and safety of the drug were independent of the degree of cardiovascular risk [1, 2]. MedChem Express HY-B0612
      Membrane Tranporter/Ion Channel MedChem Express HY-B0612
      Membrane Tranporter/Ion Channel; MedChem Express HY-B0612

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module

Density: 1.2±0.1 g/cm3
Boiling Point: 712.5±60.0 °C at 760 mmHg
Vapour Pressure: 0.0±2.3 mmHg at 25°C
Enthalpy of Vaporization: 104.2±3.0 kJ/mol
Flash Point: 384.7±32.9 °C
Index of Refraction: 1.580
Molar Refractivity: 172.9±0.3 cm3
#H bond acceptors: 9
#H bond donors: 1
#Freely Rotating Bonds: 14
#Rule of 5 Violations: 2
ACD/LogP: 8.04
ACD/LogD (pH 5.5): 4.33
ACD/BCF (pH 5.5): 241.29
ACD/KOC (pH 5.5): 275.93
ACD/LogD (pH 7.4): 5.88
ACD/BCF (pH 7.4): 8435.49
ACD/KOC (pH 7.4): 9646.34
Polar Surface Area: 114 Å2
Polarizability: 68.5±0.5 10-24cm3
Surface Tension: 46.7±3.0 dyne/cm
Molar Volume: 519.7±3.0 cm3

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