ChemSpider 2D Image | Domitor | C13H17ClN2

Domitor

  • Molecular FormulaC13H17ClN2
  • Average mass236.740 Da
  • Monoisotopic mass236.108032 Da
  • ChemSpider ID61867

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

(±)-4-(a,2,3-Trimethylbenzyl)imidazole Monohydrochloride
106807-72-1 [RN]
1H-Imidazole, 4-[1-(2,3-dimethylphenyl)ethyl]-, hydrochloride (1:1) [ACD/Index Name]
4-[(a-Methyl)-2,3-dimethylbenzyl]imidazole Monohydrochloride
4-[1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole hydrochloride
4-[1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole hydrochloride (1:1) [ACD/IUPAC Name]
4-[1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole Monohydrochloride
4-[1-(2,3-Diméthylphényl)éthyl]-1H-imidazole, chlorhydrate (1:1) [French] [ACD/IUPAC Name]
4-[1-(2,3-Dimethylphenyl)ethyl]-1H-imidazolhydrochlorid (1:1) [German] [ACD/IUPAC Name]
86347-15-1 [RN]
More...

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

BH210P244U [DBID]
UNII:BH210P244U [DBID]
1018WH7F9I [DBID]
CCRIS 4693 [DBID]
D01205 [DBID]
MPV 785 [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Bio Activity:

      7-TM Receptors Tocris Bioscience 5160
      Adrenergic Alpha-2 Receptors Tocris Bioscience 5160
      Adrenergic Receptor MedChem Express HY-17034B
      Adrenergic Receptors Tocris Bioscience 5160
      GPCR/G protein MedChem Express HY-17034B
      GPCR/G protein; MedChem Express HY-17034B
      Medetomidine Hydrochloride is an agonist of adrenergic alpha-2 receptor, which is used in veterinary medicine for its analgesic and sedative properties. MedChem Express
      Medetomidine Hydrochloride is an agonist of adrenergic alpha-2 receptor, which is used in veterinary medicine for its analgesic and sedative properties.; Target: Adrenergic alpha-2 Receptor; Medetomidine, acting at alpha(2A) adrenoceptors, must be present during the encoding process to decrease discrete cue fear memory; however, its ability to suppress contextual memory is likely the result of blocking the consolidation process [1]. MedChem Express HY-17034B
      Medetomidine Hydrochloride is an agonist of adrenergic alpha-2 receptor, which is used in veterinary medicine for its analgesic and sedative properties.;Target: Adrenergic alpha-2 ReceptorMedetomidine, acting at alpha(2A) adrenoceptors, must be present during the encoding process to decrease discrete cue fear memory; however, its ability to suppress contextual memory is likely the result of blocking the consolidation process [1]. Medetomidine had no analgesic effects in alpha(2A)-adrenoceptor KO mice [2]. Medetomidine was effective in blocking these sympathomimetic actions of cocaine even in all 7 subjects who were homozygous for the Del322-325 polymorphism in the alpha2C AR, a loss-of-function mutation that is highly enriched in blacks [3]. MedChem Express HY-17034B
      Potent, highly selective ?2 agonist Tocris Bioscience 5160
      Potent, highly selective ?2-adrenoceptor agonist (Ki values are 1.08 and 1750 nM for ?2- and ?1-adrenoceptors respectively). Displays greater selectivity over ?1-adrenoceptors than clonidine and UK 14 ,304 (1620-, 220- and 300-fold respectively). Inhibits twitch response in electrically stimulated mouse vas deferens (pD2 = 9.0). Active in vivo; displays hypotensive, bradycardic, sedative, anxiolyti c, hypothermic and analgesic effects. Tocris Bioscience 5160
      Potent, highly selective ?2-adrenoceptor agonist (Ki values are 1.08 and 1750 nM for ?2- and ?1-adrenoceptors respectively). Displays greater selectivity over ?1-adrenoceptors than clonidine and UK 14,304 (1620-, 220- and 300-fold respectively). Inhibits twitch response in electrically stimulated mouse vas deferens (pD2 = 9.0). Active in vivo; displays hypotensive, bradycardic, sedative, anxiolytic, hypothermic and analgesic effects. Tocris Bioscience 5160
      Potent, highly selective alpha2 agonist Tocris Bioscience 5160
      Potent, highly selective alpha2-adrenoceptor agonist (Ki values are 1.08 and 1750 nM for alpha2- and alpha1-adrenoceptors respectively). Displays greater selectivity over alpha1-adrenoceptors than clonidine and UK 14,304 (1620-, 220- and 300-fold respectively). Inhibits twitch response in electrically stimulated mouse vas deferens (pD2 = 9.0). Active in vivo; displays hypotensive, bradycardic, sedative, anxiolytic, hypothermic and analgesic effects. Tocris Bioscience 5160
      Potent, highly selective alpha2-adrenoceptor agonist (Ki values are 1.08 and 1750 nM for alpha2- and alpha1-adrenoceptors respectively). Displays greater selectivity over alpha1-adrenoceptors than clonidine and UK 14,304 (1620-, 220- and 300-fold respectively). Inhibits twitch response in electrically stimulated mouse vas deferens (pD2 = 9.0). Active in vivo; displays hypotensive, bradycardic, sedative, anxiolytic, hypothermic and analgesic effects. Active Isomer also available. Tocris Bioscience 5160

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

No predicted properties have been calculated for this compound.

Click to predict properties on the Chemicalize site


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