ChemSpider 2D Image | Lomefloxacin hydrochloride | C17H20ClF2N3O3

Lomefloxacin hydrochloride

  • Molecular FormulaC17H20ClF2N3O3
  • Average mass387.809 Da
  • Monoisotopic mass387.116119 Da
  • ChemSpider ID61883

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

(±)-1-Ethyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic Acid Monohydrochloride
1-Ethyl-6,8-difluor-7-(3-methyl-1-piperazinyl)-4-oxo-1,4-dihydro-3-chinolincarbonsäurehydrochlorid (1:1) [German] [ACD/IUPAC Name]
1-Ethyl-6,8-difluor-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydrochinolin-3-carbonsäurehydrochlorid
1-Ethyl-6,8-difluoro-7-(3-methyl-1-piperazinyl)-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid hydrochloride (1:1) [ACD/IUPAC Name]
1-ethyl-6,8-difluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride
1-Ethyl-6,8-difluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride (1:1)
3-Quinolinecarboxylic acid, 1-ethyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-, hydrochloride (1:1) [ACD/Index Name]
3-Quinolinecarboxylic acid, 1-ethyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-, monohydrochloride
98079-52-8 [RN]
9VC7S3ZXXB
More...

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

SC 47111 [DBID]
C08053 [DBID]
CCRIS 2581 [DBID]
D00873 [DBID]
EU-0100678 [DBID]
L2906_SIGMA [DBID]
NY 198 [DBID]
NY-198 [DBID]
Prestwick_581 [DBID]
SC-47111 [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Target Organs:

      Topoisomerase inhibitor TargetMol T1625

    • Chemical Class:

      The hydrochloride salt of lomefloxacin. It is administered by mouth to treat bacterial infections including bronchitis and urinary tract infections. It is also used topically as eye drops for the trea tment of bacterial conjunctivitis, and as ear drops for the treatment of otitis externa and otitis media. ChEBI https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:6518, CHEBI:6518

    • Bio Activity:

      Antibacterial MedChem Express HY-B0455
      Anti-infection MedChem Express HY-B0455
      Anti-infection; MedChem Express HY-B0455
      DNA Damage/DNA Repair TargetMol T1625
      Lomefloxacin HCl is a fluoroquinolone antibiotic. MedChem Express
      Lomefloxacin HCl is a fluoroquinolone antibiotic.; Target: Antibacterial; Lomefloxacin is a bactericidal fluoroquinolone agent with activity against a wide range of gram-negative and gram-positive organisms. MedChem Express HY-B0455
      Lomefloxacin HCl is a fluoroquinolone antibiotic.;Target: AntibacterialLomefloxacin is a bactericidal fluoroquinolone agent with activity against a wide range of gram-negative and gram-positive organisms. The bactericidal action of lomefloxacin results from interference with the activity of the bacterial enzymes DNA gyrase and topoisomerase IV, which are needed for the transcription and replication of bacterial DNA. DNA gyrase appears to be the primary quinolone target for gram-negative bacteria. Topoisomerase IV appears to be the preferential target in gram-positive organisms. Interference with these two topoisomerases results in strand breakage of the bacterial chromosome, supercoiling, and resealing. As a result DNA replication and transcription is inhibited [1]. MedChem Express HY-B0455
      Topoisomerase II TargetMol T1625

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

No predicted properties have been calculated for this compound.

Click to predict properties on the Chemicalize site


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