ChemSpider 2D Image | Cediranib maleate | C29H31FN4O7

Cediranib maleate

  • Molecular FormulaC29H31FN4O7
  • Average mass566.577 Da
  • Monoisotopic mass566.217651 Da
  • ChemSpider ID9401887

  • Double-bond stereo - Double-bond stereo

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

(2Z)-2-Butendisäure --4-[(4-fluor-2-methyl-1H-indol-5-yl)oxy]-6-methoxy-7-[3-(1-pyrrolidinyl)propoxy]chinazolin (1:1) [German] [ACD/IUPAC Name]
4-[(4-Fluoro-2-methyl-1H-indol-5-yl)oxy]-6-methoxy-7-[3-(1-pyrrolidinyl)propoxy]quinazoline (2Z)-2-butenedioate (1:1) [ACD/IUPAC Name]
857036-77-2 [RN]
Acide (2Z)-2-butènedioïque - 4-[(4-fluoro-2-méthyl-1H-indol-5-yl)oxy]-6-méthoxy-7-[3-(1-pyrrolidinyl)propoxy]quinazoline (1:1) [French] [ACD/IUPAC Name]
Cediranib maleate [USAN]
Quinazoline, 4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-6-methoxy-7-[3-(1-pyrrolidinyl)propoxy]-, (2Z)-2-butenedioate (1:1) [ACD/Index Name]
Recentin [Trade name]
(2Z)-BUT-2-ENEDIOIC ACID; 4-[(4-FLUORO-2-METHYL-1H-INDOL-5-YL)OXY]-6-METHOXY-7-[3-(PYRROLIDIN-1-YL)PROPOXY]QUINAZOLINE
4-((4-Fluoro-2-methyl-1H-indol-5-yl)oxy)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazoline maleate
4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-6-methoxy-7-(3-1-pyrrolidinylpropoxy)quinazoline
More...

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

68AYS9A614 [DBID]
AZD2171 maleate [DBID]
UNII:68AYS9A614 [DBID]
UNII-68AYS9A614 [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Bio Activity:

      Cediranib (AZD2171) maleate is a highly potent VEGFR(KDR) inhibitor with IC50 of <1 nM, also inhibits Flt1/4 with IC50 of 5 nM/?3 nM, similar activity against c-Kit and PDGFR?, 36-, 110-fold and >1000-fold selective more for VEGFR than PDGFR-?, CSF-1R and Flt3.; IC50 value: 0.5 nM (VEGFR2); 5 nM/?3 nM(Flt1/4) [1]; Target: VEGFR2; Flt1/4; in vitro: Cediranib maleate inhibits VEGF-stimulated proliferation with IC50 of 0.4 nM. MedChem Express HY-13049
      Protein Tyrosine Kinase/RTK MedChem Express HY-13049
      Protein Tyrosine Kinase/RTK; MedChem Express HY-13049
      VEGFR MedChem Express HY-13049

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

No predicted properties have been calculated for this compound.

Click to predict properties on the Chemicalize site


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