ChemSpider 2D Image | Aclidinium bromide | C26H30BrNO4S2

Aclidinium bromide

  • Molecular FormulaC26H30BrNO4S2
  • Average mass564.555 Da
  • Monoisotopic mass563.079956 Da
  • ChemSpider ID9694529
  • Charge - Charge

    defined stereocentres - 1 of 3 defined stereocentres


More details:



Featured data source



Validated by Experts, Validated by Users, Non-Validated, Removed by Users

(3R)-3-[2-Hydroxy(di-2-thienyl)acetoxy]-1-(3-phenoxypropyl)-1-azoniabicyclo[2.2.2]octanbromid [German] [ACD/IUPAC Name]
(3R)-3-[2-Hydroxy(di-2-thienyl)acetoxy]-1-(3-phenoxypropyl)-1-azoniabicyclo[2.2.2]octane bromide [ACD/IUPAC Name]
1-Azoniabicyclo[2.2.2]octane, 3-[(2-hydroxy-2,2-di-2-thienylacetyl)oxy]-1-(3-phenoxypropyl)-, bromide, (3R)- (1:1) [ACD/Index Name]
320345-99-1 [RN]
Aclidinium bromide [USAN] [Wiki]
Bromure de (3R)-3-[2-hydroxy-2,2-di(2-thiényl)acétoxy]-1-(3-phénoxypropyl)-1-azoniabicyclo[2.2.2]octane [French] [ACD/IUPAC Name]
Tudorza Pressair
(3R)-3-(2-Hydroxy-2,2-di(thiophen-2-yl)acetoxy)-1-(3-phenoxypropyl)quinuclidin-1-ium bromide
[(3R)-1-(3-phenoxypropyl)-1-azoniabicyclo[2.2.2]octan-3-yl] 2-hydroxy-2,2-dithiophen-2-ylacetate and bromide
[(3R)-1-(3-phenoxypropyl)quinuclidin-1-ium-3-yl] 2-hydroxy-2,2-bis(2-thienyl)acetate bromide
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  • Experimental Physico-chemical Properties
  • Miscellaneous
    • Safety:

      IRRITANT Matrix Scientific 099911
    • Bio Activity:

      Aclidinium Bromide(LAS 34273; LAS-W 330) is a long-acting, inhaled muscarinic antagonist as a maintenance treatment for chronic obstructive pulmonary disease (COPD). MedChem Express HY-14144, http://www.medchemexpress.com/Cisapride.html
      Aclidinium Bromide(LAS 34273; LAS-W 330) is a long-acting, inhaled muscarinic antagonist as a maintenance treatment for chronic obstructive pulmonary disease (COPD). ;IC50 value:;Target: M3 receptorPreclinically, aclidinium showed potent antagonism of human muscarinic receptors, with a long residence time at M3 receptors and a shorter residence time at M2 receptors, indicating the potential to provide sustained bronchodilation. Aclidinium is rapidly hydrolysed in human plasma, unlike other currently available antimuscarinics including tiotropium. Early clinical studies in healthy subjects have confirmed the low systemic bioavailability and favourable safety profile of single and multiple doses of aclidinium. In a subsequent Phase IIb study, which included 464 patients with moderate to severe COPD, aclidinium displayed long-lasting bronchodilatory activity and was well tolerated. MedChem Express HY-14144
      GPCR/G protein MedChem Express HY-14144
      GPCR/G protein; Neuronal Signaling; MedChem Express HY-14144
      mAChR MedChem Express HY-14144

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module

No predicted properties have been calculated for this compound.

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