ChemSpider 2D Image | Platelet-activating factor | C26H54NO7P

Platelet-activating factor

  • Molecular FormulaC26H54NO7P
  • Average mass523.683 Da
  • Monoisotopic mass523.363770 Da
  • ChemSpider ID97241
  • defined stereocentres - 1 of 1 defined stereocentres


More details:






Validated by Experts, Validated by Users, Non-Validated, Removed by Users

(2R)-2-Acetoxy-3-(hexadecyloxy)propyl 2-(trimethylammonio)ethyl phosphate [ACD/IUPAC Name]
(2R)-2-Acetoxy-3-(hexadecyloxy)propyl-2-(trimethylammonio)ethylphosphat [German] [ACD/IUPAC Name]
2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine
42EWD89I80
74389-68-7 [RN]
AcGEPC
Ethanaminium, 2-[[[(2R)-2-(acetyloxy)-3-(hexadecyloxy)propoxy]hydroxyphosphinyl]oxy]-N,N,N-trimethyl-, inner salt [ACD/Index Name]
PAF
PAF Acether
PAF(C16)
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Validated by Experts, Validated by Users, Non-Validated, Removed by Users

P4904_SIGMA [DBID]
P7568_SIGMA [DBID]
P9525_SIGMA [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous
    • Chemical Class:

      A 2-acetyl-1-alkyl-<ital>sn</ital>-glycero-3-phosphocholine betaine which has hexadecyl as the alkyl group. PAF is a potent phospholipid activator and mediator of many leukocyte functions, including p latelet aggregation, inflammation, and anaphylaxis. ChEBI CHEBI:44811
    • Bio Activity:

      7-TM Receptors Tocris Bioscience 2940
      Endogenous platelet-activating factor (PAF) Tocris Bioscience 2940
      Endogenous platelet-activating factor (PAF) and ligand for PAF receptors. Produced by inflammatory cells and a potent chemoattractant for polymorphonuclear neutrophils. Induces increased vascular perm eability. Tocris Bioscience 2940
      Endogenous platelet-activating factor (PAF) and ligand for PAF receptors. Produced by inflammatory cells and a potent chemoattractant for polymorphonuclear neutrophils. Induces increased vascular permeability. Tocris Bioscience 2940
      Platelet-activating Factor (PAF) Receptors Tocris Bioscience 2940

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module

Density:
Boiling Point:
Vapour Pressure:
Enthalpy of Vaporization:
Flash Point:
Index of Refraction:
Molar Refractivity:
#H bond acceptors: 8
#H bond donors: 1
#Freely Rotating Bonds: 26
#Rule of 5 Violations: 1
ACD/LogP: 3.94
ACD/LogD (pH 5.5): 3.06
ACD/BCF (pH 5.5): 173.68
ACD/KOC (pH 5.5): 2067.00
ACD/LogD (pH 7.4): 3.06
ACD/BCF (pH 7.4): 173.68
ACD/KOC (pH 7.4): 2067.07
Polar Surface Area: 104 Å2
Polarizability:
Surface Tension:
Molar Volume:

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