ChemSpider 2D Image | RALIMETINIB MESYLATE | C26H37FN6O6S2

RALIMETINIB MESYLATE

  • Molecular FormulaC26H37FN6O6S2
  • Average mass612.737 Da
  • Monoisotopic mass612.219971 Da
  • ChemSpider ID9745575

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

3-(2,2-Dimethylpropyl)-5-[4-(4-fluorophenyl)-2-(2-methyl-2-propanyl)-1H-imidazol-5-yl]-3H-imidazo[4,5-b]pyridin-2-amine methanesulfonate (1:2) [ACD/IUPAC Name]
3H-Imidazo[4,5-b]pyridin-2-amine, 5-[2-(1,1-dimethylethyl)-4-(4-fluorophenyl)-1H-imidazol-5-yl]-3-(2,2-dimethylpropyl)-, methanesulfonate (1:2) [ACD/Index Name]
5-[2-tert-butyl-4-(4-fluorophenyl)-1H-imidazol-5-yl]-3-(2,2-dimethylpropyl)-3H-imidazo[4,5-b]pyridin-2-amine; bis(methanesulfonic acid)
862507-23-1 [RN]
Acide méthanesulfonique - 3-(2,2-diméthylpropyl)-5-[4-(4-fluorophényl)-2-(2-méthyl-2-propanyl)-1H-imidazol-5-yl]-3H-imidazo[4,5-b]pyridin-2-amine (2:1) [French] [ACD/IUPAC Name]
LSN2322600
LY2228820 (mesylate)
LY2228820 dimesylate
Methansulfonsäure --3-(2,2-dimethylpropyl)-5-[4-(4-fluorphenyl)-2-(2-methyl-2-propanyl)-1H-imidazol-5-yl]-3H-imidazo[4,5-b]pyridin-2-amin (2:1) [German] [ACD/IUPAC Name]
QUW7B71FO9
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  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Bio Activity:

      LY2228820 is a novel and potent p38MAPK inhibitor (the IC50 for p38?MAPK and p38?MAPK were 7 nM and 3 nM, respectively).; IC50 value: 7/3 nM(p38?/p38? MAPK) [1]; Target: p38MAPK; in vitro: LY2228820 inhibits p38?, as well as the level of phosphoMAPKAPK-2 (pMK2) in RAW 264.7 cells, with IC50 values of 7 nM and 34.3 nM, respectively. MedChem Express HY-13241
      MAPK MedChem Express HY-13241
      MAPK ; MedChem Express HY-13241
      p38 MAPK MedChem Express HY-13241

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

No predicted properties have been calculated for this compound.

Click to predict properties on the Chemicalize site


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