Found 1 result

Search term: 129318-43-0 (Found by approved synonym)
ChemSpider 2D Image | Alendronate sodium | C4H12NNaO7P2

Alendronate sodium

  • Molecular FormulaC4H12NNaO7P2
  • Average mass271.078 Da
  • Monoisotopic mass270.998657 Da
  • ChemSpider ID56669

  • Charge - Charge

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

(4-Amino-1-hydroxybutylidene)bisphosphonic acid monosodium salt
129318-43-0 [RN]
Alendronate sodium [USAN]
Alendronic acid sodium salt
Hydrogéno(4-amino-1-hydroxy-1-phosphonobutyl)phosphonate de sodium [French] [ACD/IUPAC Name]
Monosodium alendronate
Natriumhydrogen(4-amino-1-hydroxy-1-phosphonobutyl)phosphonat [German] [ACD/IUPAC Name]
Phosphonic acid, (4-amino-1-hydroxybutylidene)bis-, sodium salt (1:1) [ACD/Index Name]
Sodium hydrogen (4-amino-1-hydroxy-1-phosphonobutyl)phosphonate [ACD/IUPAC Name]
[129318-43-0] [RN]
More...

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

4988K7X26P [DBID]
G-704650 [DBID]
GTH-42 [DBID]
L-670452 [DBID]
MER-103 [DBID]
MK 217 [DBID]
MK-0217 [DBID]
MK-217 [DBID]
UNII:4988K7X26P [DBID]
UNII-4988K7X26P [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Bio Activity:

      Enzymes Tocris Bioscience 4014
      Inhibitor of farnesyl diphosphate synthase (FPPS) and osteoclast-mediated bone resorption Tocris Bioscience 4014
      Osteoclast-mediated bone resorption inhibitor. Binds and blocks farnesyl diphosphate synthase (FPPS) in the HMG-CoA pathway (IC50 = 460 nM for recombinant human FPPS); causes macrophage apoptosis. Inh ibits prenylation and sterol biosynthesis in purified osteoclasts. Tocris Bioscience 4014
      Osteoclast-mediated bone resorption inhibitor. Binds and blocks farnesyl diphosphate synthase (FPPS) in the HMG-CoA pathway (IC50 = 460 nM for recombinant human FPPS); causes macrophage apoptosis. Inhibits prenylation and sterol biosynthesis in purified osteoclasts. Tocris Bioscience 4014
      Other Synthases/Synthetases Tocris Bioscience 4014
      Synthases/Synthetases Tocris Bioscience 4014

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

No predicted properties have been calculated for this compound.

Click to predict properties on the Chemicalize site


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