Found 1 result

Search term: 23541-50-6 (Found by approved synonym)
ChemSpider 2D Image | Daunorubicin hydrochloride | C27H30ClNO10

Daunorubicin hydrochloride

  • Molecular FormulaC27H30ClNO10
  • Average mass563.981 Da
  • Monoisotopic mass563.155823 Da
  • ChemSpider ID56512

  • defined stereocentres - 6 of 6 defined stereocentres

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

(-)-Daunorubicin
(1S,3S)-3-Acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-1-tetracenyl 3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranoside hydrochloride (1:1) [ACD/IUPAC Name]
(1S,3S)-3-Acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-1-tetracenyl-3-amino-2,3,6-tridesoxy-α-L-lyxo-hexopyranosidhydrochlorid (1:1) [German] [ACD/IUPAC Name]
(1S,3S)-3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyranoside hydrochloride
(1S,3S)-3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranoside hydrochloride
(1S,3S)-3-Acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranoside hydrochloride (1:1)
(8S,10S)-8-Acetyl-10-[(3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione Hydrochloride
(8S,10S)-8-acetyl-10-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy}-6,8,11-trihydroxy-1-methoxy-5,7,8,9,10,12-hexahydrotetracene-5,12-dione hydrochloride
(8S,10S)-8-Acetyl-10-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-6,8,11-trihydroxy-1-methoxy-7,8,9,10-tetrahydrotetracen-5,12-dionhydrochlorid
(8S,10S)-8-acétyl-10-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-méthyltétrahydro-2H-pyran-2-yl]oxy}-6,8,11-trihydroxy-1-méthoxy-7,8,9,10-tétrahydrotétracène-5,12-dione chlorhydrate
More...

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

4229221 [DBID]
AI3-44887 [DBID]
CCRIS 915 [DBID]
D01264 [DBID]
MLS000069508 [DBID]
NCGC00024246-03 [DBID]
RP-13057 [DBID]
SMR000058559 [DBID]
W4013_SIGMA [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Appearance:

      orange-red powder OU Chemical Safety Data (No longer updated) More details

    • Toxicity:

      ORL-RAT LD50 290 mg kg-1, ORL-MUS LD50 205 mg kg-1, IVN-MUS LD50 26 mg kg-1 OU Chemical Safety Data (No longer updated) More details

    • Safety:

      Safety glasses, adequate ventilation, gloves. OU Chemical Safety Data (No longer updated) More details

    • Bio Activity:

      <p>Antibiotic. RNA and DNA synthesis inhibitor. Inhibits topoisomerase I and II and intercalates into DNA to induce DNA damage.</p> <p>Shows potent anticancer activity.</p> Hello Bio HB4376
      <p>Antibiotic. RNA and DNA synthesis inhibitor. Inhibits topoisomerase I and II and intercalates into DNA to induce DNA damage.</p> <p>Shows potent anticancer activity.</p> <p>Recently investigated as part of COVID-19 compound repurposing.</p> Hello Bio HB4376
      ADCs cytotoxin MedChem Express HY-13062
      ADCs cytotoxin Topoisomerase MedChem Express HY-13062
      Antibiotic. RNA and DNA synthesis inhibitor. Hello Bio HB4376
      Antibiotics Hello Bio HB4376
      Antibody-drug conjugates/ADCs Related MedChem Express HY-13062
      Antibody-drug conjugates/ADCs Related; Cell Cycle/DNA Damage; MedChem Express HY-13062
      Daunorubicin Hcl inhibits both DNA and RNA synthesis and inhibits DNA synthesis with Ki of 0.02 ?M. MedChem Express HY-13062
      Enzymes/Isomerase/DNA Topoisomerase/Type 1 Hello Bio HB4376
      Enzymes/Isomerase/DNA Topoisomerase/Type 2 Hello Bio HB4376

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

No predicted properties have been calculated for this compound.

Click to predict properties on the Chemicalize site


Advertisement