Found 1 result

Search term: Psi (Found by approved synonym)
ChemSpider 2D Image | PSI | C32H50N4O8

PSI

  • Molecular FormulaC32H50N4O8
  • Average mass618.761 Da
  • Monoisotopic mass618.362854 Da
  • ChemSpider ID8136267

  • defined stereocentres - 5 of 5 defined stereocentres

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

(4S)-4-{[(2S,3S)-2-{[(Benzyloxy)carbonyl]amino}-3-méthylpentanoyl]amino}-5-{[(2S)-1-{[(2S)-4-méthyl-1-oxo-2-pentanyl]amino}-1-oxo-2-propanyl]amino}-5-oxopentanoate de 2-méthyl-2-propanyle (non-preferr ed name) [French] [ACD/IUPAC Name]
158442-41-2 [RN]
2-Methyl-2-propanyl (4S)-4-{[(2S,3S)-2-{[(benzyloxy)carbonyl]amino}-3-methylpentanoyl]amino}-5-{[(2S)-1-{[(2S)-4-methyl-1-oxo-2-pentanyl]amino}-1-oxo-2-propanyl]amino}-5-oxopentanoate (non-preferred n ame) [ACD/IUPAC Name]
2-Methyl-2-propanyl-(4S)-4-{[(2S,3S)-2-{[(benzyloxy)carbonyl]amino}-3-methylpentanoyl]amino}-5-{[(2S)-1-{[(2S)-4-methyl-1-oxo-2-pentanyl]amino}-1-oxo-2-propanyl]amino}-5-oxopentanoat (non-preferred na me) [German] [ACD/IUPAC Name]
MFCD00671409
PSI
tert-Butyl (4S)-4-{[(2S,3S)-2-{[(benzyloxy)carbonyl]amino}-3-methylpentanoyl]amino}-5-{[(2S)-1-{[(2S)-4-methyl-1-oxopentan-2-yl]amino}-1-oxopropan-2-yl]amino}-5-oxopentanoate (non-preferred name)
Z-Ile-Glu(O-t-butyl)-Ala-Leucinal
(S)-tert-butyl 4-((2S,3S)-2-(((benzyloxy)carbonyl)amino)-3-methylpentanamido)-5-(((S)-1-(((S)-4-methyl-1-oxopentan-2-yl)amino)-1-oxopropan-2-yl)amino)-5-oxopentanoate
[158442-41-2] [RN]
More...
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Bio Activity:

      Enzymes Tocris Bioscience 4045
      Proteases Tocris Bioscience 4045
      Proteasome Tocris Bioscience 4045
      Proteasome inhibitor. Also prevents activation of NF-?B Tocris Bioscience 4045
      Proteasome inhibitor. Also prevents activation of NF-kappaB Tocris Bioscience 4045
      Proteasome inhibitor; inhibits chymotrypsin-like activity of the proteasome. Causes dopaminergic cell death in vitro. Prevents activation of NF-?B in response to TNF-? and okadaic acid (Cat. No. 1136) by inhibiting I?B-? degradation. Also inhibits NO production by LPS-activated macrophages. Tocris Bioscience 4045
      Proteasome inhibitor; inhibits chymotrypsin-like activity of the proteasome. Causes dopaminergic cell death in vitro. Prevents activation of NF-?B in response to TNF-? and okadaic acid (Cat. No. 1136) by inhibiting I?B-? degradation. Also inhibits NO production by LPS-activated macrophages. Tocris Bioscience 4045
      Proteasome inhibitor; inhibits chymotrypsin-like activity of the proteasome. Causes dopaminergic cell death in vitro. Prevents activation of NF-kappaB in response to TNF-alpha and okadaic acid (Cat. No. 1136) by inhibiting IkappaB-alpha degradation. Also inhibits NO production by LPS-activated macrophages. Tocris Bioscience 4045

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

Density: 1.1±0.1 g/cm3
Boiling Point: 844.2±65.0 °C at 760 mmHg
Vapour Pressure: 0.0±3.1 mmHg at 25°C
Enthalpy of Vaporization: 122.7±3.0 kJ/mol
Flash Point: 464.4±34.3 °C
Index of Refraction: 1.510
Molar Refractivity: 164.9±0.3 cm3
#H bond acceptors: 12
#H bond donors: 4
#Freely Rotating Bonds: 20
#Rule of 5 Violations: 3
ACD/LogP: 5.79
ACD/LogD (pH 5.5): 3.54
ACD/BCF (pH 5.5): 286.15
ACD/KOC (pH 5.5): 1995.43
ACD/LogD (pH 7.4): 3.54
ACD/BCF (pH 7.4): 286.04
ACD/KOC (pH 7.4): 1994.64
Polar Surface Area: 169 Å2
Polarizability: 65.4±0.5 10-24cm3
Surface Tension: 41.9±3.0 dyne/cm
Molar Volume: 551.6±3.0 cm3

Click to predict properties on the Chemicalize site


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