Found 1 result

Search term: 19031468 (Found by CSID)
ChemSpider 2D Image | NNC 55-0396 | C30H40Cl2FN3O2

NNC 55-0396

  • Molecular FormulaC30H40Cl2FN3O2
  • Average mass564.562 Da
  • Monoisotopic mass563.248169 Da
  • ChemSpider ID19031468

  • defined stereocentres - 2 of 2 defined stereocentres

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

(1S,2S)-2-(2-{[3-(1H-Benzimidazol-2-yl)propyl](methyl)amino}ethyl)-6-fluor-1-isopropyl-1,2,3,4-tetrahydro-2-naphthalinyl-cyclopropancarboxylatdihydrochlorid [German] [ACD/IUPAC Name]
(1S,2S)-2-(2-{[3-(1H-Benzimidazol-2-yl)propyl](methyl)amino}ethyl)-6-fluoro-1-isopropyl-1,2,3,4-tetrahydro-2-naphthalenyl cyclopropanecarboxylate dihydrochloride [ACD/IUPAC Name]
(1S,2S)-2-(2-{[3-(1H-Benzimidazol-2-yl)propyl](methyl)amino}ethyl)-6-fluoro-1-isopropyl-1,2,3,4-tetrahydronaphthalen-2-yl cyclopropanecarboxylate dihydrochloride
357400-13-6 [RN]
Cyclopropanecarboxylate de (1S,2S)-2-(2-{[3-(1H-benzimidazol-2-yl)propyl](méthyl)amino}éthyl)-6-fluoro-1-isopropyl-1,2,3,4-tétrahydro-2-naphtalényle, dichlorhydrate [French] [ACD/IUPAC Name]
Cyclopropanecarboxylic acid, (1S,2S)-2-[2-[[3-(1H-benzimidazol-2-yl)propyl]methylamino]ethyl]-6-fluoro-1,2,3,4-tetrahydro-1-(1-methylethyl)-2-naphthalenyl ester, hydrochloride (1:2) [ACD/Index Name]
NNC 55-0396
NNC 55-0396 dihydrochloride
NNC-55-0396
(1S,2S)-2-(2-((3-(1H-Benzo[d]imidazol-2-yl)propyl)(methyl)amino)ethyl)-6-fluoro-1-isopropyl-1,2,3,4-tetrahydronaphthalen-2-yl cyclopropanecarboxylate dihydrochloride
More...

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

0A7CE46ERM [DBID]
UNII:0A7CE46ERM [DBID]
UNII-0A7CE46ERM [DBID]
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Chemical Class:

      The dihydrochloride salt of NNC 55-0396. It is a stable analogue of mibefradil and a highly selective T-type calcium channel blocker. ChEBI CHEBI:194301

    • Bio Activity:

      Calcium Channel MedChem Express HY-50722
      Calcium Channels Tocris Bioscience 2268
      Highly selective Ca2+ channel blocker (T-type) Tocris Bioscience 2268
      Highly selective T-type calcium channel blocker. Displays IC50 values of 6.8 and > 100 ?M for inhibition of Cav3.1 T-type channels and HVA currents respectively in INS-1 cells. Tocris Bioscience 2268
      Highly selective T-type calcium channel blocker. Displays IC50 values of 6.8 and > 100 muM for inhibition of Cav3.1 T-type channels and HVA currents respectively in INS-1 cells. Tocris Bioscience 2268
      Ion Channels Tocris Bioscience 2268
      Membrane Transporter/Ion Channel MedChem Express HY-50722
      Membrane Transporter/Ion Channel; MedChem Express HY-50722
      NNC 55-0396, Mibefradil derivative, is a highly selective T-type calcium channel blocker; displays IC50 values of 6.8 and > 100 ?M for inhibition of Cav3.1 T-type channels and HVA currents respectively in INS-1 cells. MedChem Express HY-50722
      Voltage-gated Calcium Channels Tocris Bioscience 2268

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

No predicted properties have been calculated for this compound.

Click to predict properties on the Chemicalize site


Advertisement