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Search term: 26404850 (Found by CSID)
ChemSpider 2D Image | JW 480 | C22H23NO2

JW 480

  • Molecular FormulaC22H23NO2
  • Average mass333.423 Da
  • Monoisotopic mass333.172882 Da
  • ChemSpider ID26404850

More details:

Validated by Experts, Validated by Users, Non-Validated, Removed by Users

[2-(2-Naphtyl)éthyl]carbamate de 2-isopropylphényle [French] [ACD/IUPAC Name]
1354359-53-7 [RN]
2-Isopropylphenyl [2-(2-naphthyl)ethyl]carbamate [ACD/IUPAC Name]
2-Isopropylphenyl-[2-(2-naphthyl)ethyl]carbamat [German] [ACD/IUPAC Name]
Carbamic acid, N-[2-(2-naphthalenyl)ethyl]-, 2-(1-methylethyl)phenyl ester [ACD/Index Name]
JW 480
(2-propan-2-ylphenyl) N-(2-naphthalen-2-ylethyl)carbamate
[1354359-53-7] [RN]
2-(PROPAN-2-YL)PHENYL N-[2-(NAPHTHALEN-2-YL)ETHYL]CARBAMATE
2-Isopropylphenyl (2-(naphthalen-2-yl)ethyl)carbamate
More...
  • Experimental Physico-chemical Properties
  • Miscellaneous

    • Safety:

      Sold under license from The Scripps Research Institute. Tocris Bioscience 4327

    • Bio Activity:

      Enzymes Tocris Bioscience 4327
      Hydrolases Tocris Bioscience 4327
      Other Hydrolases Tocris Bioscience 4327
      Potent and selective inhibitor of serine hydrolase KIAA1363 (AADACL1) Tocris Bioscience 4327
      Potent and selective inhibitor of the serine hydrolase enzyme KIAA1363 (AADACL1) (IC50 = 20 nM in mouse brain). Impairs migration, invasion, survival and tumor growth of prostate cancer cell lines in vivo. Reduces monoalkylglycerol ether (MAGE) levels. Tocris Bioscience 4327
      Potent and selective inhibitor of the serine hydrolase enzyme KIAA1363 (AADACL1) (IC50 = 20 nM in mouse brain). Impairs migration, invasion, survival and tumor growth of prostate cancer cell lines in vivo. Reduces monoalkylglycerol ether (MAGE) levels. Tocris Bioscience 4327

Predicted data is generated using the ACD/Labs Percepta Platform - PhysChem Module, version: 14.00

Density: 1.1±0.1 g/cm3
Boiling Point: 486.2±38.0 °C at 760 mmHg
Vapour Pressure: 0.0±1.2 mmHg at 25°C
Enthalpy of Vaporization: 75.2±3.0 kJ/mol
Flash Point: 247.9±26.8 °C
Index of Refraction: 1.605
Molar Refractivity: 102.3±0.3 cm3
#H bond acceptors: 3
#H bond donors: 1
#Freely Rotating Bonds: 6
#Rule of 5 Violations: 1
ACD/LogP: 5.93
ACD/LogD (pH 5.5): 5.40
ACD/BCF (pH 5.5): 7520.14
ACD/KOC (pH 5.5): 20710.60
ACD/LogD (pH 7.4): 5.40
ACD/BCF (pH 7.4): 7519.85
ACD/KOC (pH 7.4): 20709.82
Polar Surface Area: 38 Å2
Polarizability: 40.6±0.5 10-24cm3
Surface Tension: 44.4±3.0 dyne/cm
Molar Volume: 297.3±3.0 cm3

Click to predict properties on the Chemicalize site


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